SCHEMBL1370015

SCHEMBL1370015

C[N+](C)(C)CCO[PH](=O)CC(O)CO

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.44
CHRM1 P11229 8/20 0.34
CHRM3 P20309 8/20 0.34
CHRM2 P08172 7/20 0.34
CHRM4 P08173 7/20 0.34
CHRM5 P08912 6/20 0.34
CHRNB2 P17787 4/20 0.34
CHRNA4 P43681 4/20 0.34
CHRNA7 P36544 3/20 0.34
HTR1A P08908 2/20 0.34
ADRA2A P08913 1/20 0.34
ADRA1A P35348 1/20 0.34
PGR P06401 1/20 0.34
TBXA2R P21731 1/20 0.34
CHRNB4 P30926 1/20 0.34
CHRNA3 P32297 1/20 0.34
CHRNA10 Q9GZZ6 1/20 0.34
CHRNA9 Q9UGM1 1/20 0.34
GALR3 O60755 2/20 0.34
CYP2C19 P33261 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Zinc Ion SCHEMBL10604225 0.98 SMN1; SMN2 (0.43) SMN1; SMN2CHRM1CHRM3CHRM2CHRM4
SCHEMBL10602664 0.98 SMN1; SMN2 (0.43) SMN1; SMN2CHRM1CHRM3CHRM2CHRM4
SCHEMBL10606124 0.98 SMN1; SMN2 (0.43) SMN1; SMN2CHRM1CHRM3CHRM2CHRM4
SCHEMBL10604517 0.98 SMN1; SMN2 (0.43) SMN1; SMN2CHRM1CHRM3CHRM2CHRM4
Propylene Glycol SCHEMBL8861293 0.97 SMN1; SMN2 (0.42) SMN1; SMN2CHRM1CHRM3CHRM2CHRM4
SCHEMBL5357432 0.88 SMN1; SMN2 (0.37) SMN1; SMN2CHRM1CHRM3CHRM2CHRM4
SCHEMBL159440 0.77 SMN1; SMN2 (0.50) SMN1; SMN2CHRM1CHRM3CHRM2CHRM4
SCHEMBL28229216 0.77 SMN1; SMN2 (0.50) SMN1; SMN2CHRM1CHRM3CHRM2CHRM4
SCHEMBL26661989 0.77 SMN1; SMN2 (0.50) SMN1; SMN2CHRM1CHRM3CHRM2CHRM4
Iodide SCHEMBL10581935 0.76 SMN1; SMN2 (0.49) SMN1; SMN2CHRM1CHRM3CHRM2CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 637 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240156790-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING FERROPTOSIS AND TREATING EXCITOTOXIC DISORDERS THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK 2024-05-16 US claimed
US-20240115499-A1 DHA and Choline Emulsion CAPSUGEL BELGIUM NV (BE) 2024-04-11 US claimed
EP-4347605-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING FERROPTOSIS AND TREATING EXCITOTOXIC DISORDERS The Trustees of Columbia University in the City of New York (US) 2024-04-10 EP claimed
EP-4319759-A1 1-METHYLXANTHINE-BASED BIOACTIVE COMPOSITION AND METHOD OF USE THEREOF Ingenious Ingredients, LP (US) 2024-02-14 EP claimed
EP-4313056-A1 THE USE OF PARAXANTHINE TO IMPROVE PERFORMANCE IN VIDEO GAMERS PX ING, LLC (US) 2024-02-07 EP claimed
EP-4312801-A1 PARAXANTHINE-BASED COMPOSITIONS FOR PROMOTING WEIGHT LOSS PX ING, LLC (US) 2024-02-07 EP claimed
WO-2023173111-A2 INTRA-DOSAGE FORM COATINGS AND APPLICATIONS THEREOF BALCHEM CORPORATION (US) 2023-09-14 WO claimed
WO-2023150389-A1 COMPOSITIONS AND METHODS FOR INCREASING DHA AVAILABILITY CORNELL UNIVERSITY (US) 2023-08-10 WO claimed
US-20230217977-A1 DIETARY CHOLINE SUPPLEMENTATION TO REDUCE TUMOR VOLUME AND ENHANCE COGNITIVE RESPONSE DURING CANCER TREATMENT NATIONAL INSTITUTES OF HEALTH 2023-07-13 US claimed
WO-2023064511-A9 PARAXANTHINE-BASED BIOACTIVE COMPOSITION AND METHOD OF USE THEREOF Ingenious Ingredients, LP (US) 2023-06-08 WO claimed
US-6368617-B1 Dietary supplement RELIV' INTERNATIONAL, INC. 2002-04-09 US claimed
WO-2002013838-A1 SEAL-OIL-BASED PHARMACEUTICAL, COSMETIC, DERMO-COSMETIC, HYGIENE, ALIMENTARY AND PARA-ALIMENTARY (FOOD-SUPPLEMENTS) PRODUCTS; THEIR METHODS OF PREPARATION; THEIR USES AS PREVENTIVE AND/OR AS THERAPEUTIC AGENTS FUNDAÇAO ESSPRIT-ICARUS (FUNDAÇAO EUROPEIA DE INVESTIGAÇAO MEDICA), NGO; IPSS. (PT) 2002-02-21 WO claimed
EP-0803246-A1 Compositions for topical application based on thermal muds and gelling agents APR APPLIED PHARMA RESEARCH S.A. (CH) 1997-10-29 EP claimed
US-5250719-A Process for the preparation of L-α-glycerylphosphoryl-choline and of L-α-glycerylphosphorylethanolamine PRIME EUROPEAN THERAPEUTICALS S.P.A. (IT) 1993-10-05 US claimed
EP-0217765-B1 PROCESS FOR THE PREPARATION OF L-ALPHA-GLYCERYLPHOSPHORYLCHOLINE, L-ALPHA-GLYCERYLPHOSPHORYLETHANOLAMINE FROM CRUDE AND/OR DEOLEATED LECITHINS ISTITUTO CHEMIOTERAPICO ITALIANO FINE CHEMICALS S.p.A. (IT) 1990-08-16 EP claimed
EP-0186803-B1 DIACYLDERIVATIVES OF GLYCERYLPHOSPHORYLCHOLINE HAVING THERAPEUTICAL ACTIVITY, A PROCESS FOR THEIR PREPARATION AND RELATED PHARMACEUTICAL COMPOSITIONS NEOPHARMED S.p.A. (IT) 1989-09-20 EP claimed
US-4824978-A Complexes of glycerylphosphorylcholine NEOPHARMED SPA (IT) 1989-04-25 US claimed
US-4699901-A Diacyl derivatives of glycerylphosphorylcholine, their preparation, and antihyperlipidemic compositions NEOPHARMED SPA (IT) 1987-10-13 US claimed
EP-0217765-A2 Process for the preparation of L-alpha-glycerylphosphorylcholine, L-alpha-glycerylphosphorylethanolamine from crude and/or deoleated lecithins ISTITUTO CHEMIOTERAPICO ITALIANO FINE CHEMICALS S.p.A. (IT) 1987-04-08 EP claimed
EP-0186803-A2 Diacylderivatives of glycerylphosphorylcholine having therapeutical activity, a process for their preparation and related pharmaceutical compositions NEOPHARMED S.p.A. (IT) 1986-07-09 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240156790-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING FERROPTOSIS AND TREATING EXCITOTOXIC DISORDERS AIFM2, GPX1, SLC7A11 SMN1; SMN2 311/4885CHRM1 4698/4885CHRM3 4649/4885
US-20240115499-A1 DHA and Choline Emulsion LIPA, CHAT, PHOSPHO1 SMN1; SMN2 863/4885CHRM1 724/4885CHRM3 609/4885
US-20230217977-A1 DIETARY CHOLINE SUPPLEMENTATION TO REDUCE TUMOR VOLUME AND ENHANCE COGNITIVE RESPONSE DURING CANCER TREATMENT CHAT, CHKA, CHKB SMN1; SMN2 2084/4885CHRM1 56/4885CHRM3 88/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.