Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | PPOX | P50336 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10604884 | 0.88 | MEN1 (0.67) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10606237 | 0.88 | TDP1 (0.53) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10603239 | 0.83 | MEN1 (0.66) | TDP1MEN1KMT2ATTRPPOX | |
| Bifenox SCHEMBL38816 | 0.82 | TDP1 (1.00) | TDP1MEN1KMT2ATTRPPOX | |
| Bifenox SCHEMBL8541647 | 0.82 | TDP1 (1.00) | TDP1MEN1KMT2ATTRPPOX | |
| Bifenox SCHEMBL30862569 | 0.82 | TDP1 (1.00) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL9342535 | 0.82 | TDP1 (0.78) | TDP1MEN1KMT2ATTRPPOX | |
| Bifenox SCHEMBL28419037 | 0.81 | TDP1 (0.98) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10608534 | 0.81 | MEN1 (0.54) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10603393 | 0.80 | MEN1 (0.69) | TDP1MEN1KMT2ATTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0167349-B1 | META-SUBSTITUTED DIOXA-ALKANE CARBOXYLIC ACIDS, ESTERS, AMIDES AND SALTS OF DIPHENYL ETHERS | ROHM AND HAAS COMPANY (US) | 1989-08-30 | — | — | EP | disclosed |
| EP-0167349-A2 | Meta-substituted dioxa-alkane carboxylic acids, esters, amides and salts of diphenyl ethers | ROHM AND HAAS COMPANY (US) | 1986-01-08 | — | — | EP | disclosed |