Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 19/20 | 0.52 |
| ▸ | PGC | P20142 | 1/20 | 0.44 |
| ▸ | CCKBR | P32239 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10609083 | 0.91 | REN (0.57) | REN | |
| SCHEMBL9833160 | 0.88 | REN (0.51) | RENPGC | |
| SCHEMBL10611452 | 0.87 | REN (0.51) | RENPGCCCKBR | |
| SCHEMBL9831114 | 0.81 | REN (0.49) | RENPGCCCKBR | |
| SCHEMBL9832821 | 0.81 | REN (0.57) | REN | |
| SCHEMBL9832617 | 0.78 | REN (0.48) | RENPGC | |
| SCHEMBL9831316 | 0.78 | REN (0.49) | RENPGC | |
| SCHEMBL9833647 | 0.76 | REN (0.53) | REN | |
| SCHEMBL7292800 | 0.76 | REN (0.59) | REN | |
| SCHEMBL7292517 | 0.76 | REN (0.66) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4826958-A | HYPOTENSIVE AGENTS | ABBOTT LABORATORIES (US) | 1989-05-02 | — | — | US | disclosed |
| EP-0184855-A2 | Resin inhibiting compounds | ABBOTT LABORATORIES (US) | 1986-06-18 | — | — | EP | disclosed |