Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.51 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.50 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.50 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CASR | P41180 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6637800 | 0.86 | LOXL2 (0.50) | LOXL2CYP4F2CYP4A11SLC7A5ALDH1A1 | |
| SCHEMBL20032090 | 0.85 | LOXL2 (0.53) | LOXL2CYP4F2CYP4A11SLC7A5ALDH1A1 | |
| SCHEMBL5662355 | 0.84 | LOXL2 (0.51) | LOXL2CYP4F2CYP4A11SLC7A5ALDH1A1 | |
| SCHEMBL28346938 | 0.84 | HDAC4 (0.51) | LOXL2CYP4F2CYP4A11SLC7A5ALDH1A1 | |
| SCHEMBL1787505 | 0.84 | HDAC4 (0.51) | LOXL2CYP4F2CYP4A11SLC7A5ALDH1A1 | |
| SCHEMBL6934024 | 0.83 | LOXL2 (0.54) | LOXL2CYP4F2CYP4A11SLC7A5ALDH1A1 | |
| SCHEMBL14231684 | 0.83 | LOXL2 (0.54) | LOXL2CYP4F2CYP4A11SLC7A5ALDH1A1 | |
| SCHEMBL10277654 | 0.83 | LOXL2 (0.54) | LOXL2CYP4F2CYP4A11SLC7A5ALDH1A1 | |
| SCHEMBL11229041 | 0.81 | TSHR (0.52) | LOXL2CYP4F2CYP4A11SLC7A5ALDH1A1 | |
| SCHEMBL935780 | 0.81 | TSHR (0.52) | LOXL2CYP4F2CYP4A11SLC7A5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0162208-B1 | NOVEL N-SUBSTITUTED 3,4-DIHYDROPYRIMIDINE DERIVATIVES, PROCESSES FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS | SUNTORY KABUSHIKI KAISHA, also known as SUNTORY LTD. (JP) | 1989-11-23 | — | — | EP | disclosed |
| US-4683234-A | HYPOTENSIVE AGENTS, ANTI-ANGINA | SUNTORY LIMITED (JP) | 1987-07-28 | — | — | US | disclosed |
| EP-0162208-A2 | Novel N-substituted 3,4-dihydropyrimidine derivatives, processes for preparing them and pharmaceutical compositions | SUNTORY KABUSHIKI KAISHA, also known as SUNTORY LTD. (JP) | 1985-11-27 | — | — | EP | disclosed |