Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.61 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.61 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.61 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.61 |
| ▸ | DRD3 | P35462 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | PRCP | P42785 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.36 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10604555 | 0.89 | DRD3 (0.55) | OPRM1OPRL1OPRD1OPRK1DRD3 | |
| SCHEMBL10606271 | 0.88 | DRD3 (0.54) | OPRM1OPRL1OPRD1OPRK1DRD3 | |
| SCHEMBL10604043 | 0.86 | DRD3 (0.52) | OPRM1OPRL1OPRD1OPRK1DRD3 | |
| SCHEMBL10603880 | 0.85 | OPRM1 (0.59) | OPRM1OPRL1OPRD1OPRK1DRD3 | |
| SCHEMBL3018551 | 0.84 | OPRM1 (0.57) | OPRM1OPRL1OPRD1OPRK1DRD3 | |
| SCHEMBL7848116 | 0.84 | OPRM1 (0.57) | OPRM1OPRL1OPRD1OPRK1DRD3 | |
| SCHEMBL614227 | 0.83 | OPRM1 (0.68) | OPRM1OPRL1OPRD1OPRK1DRD3 | |
| SCHEMBL19475380 | 0.82 | OPRM1 (0.66) | OPRM1OPRL1OPRD1OPRK1DRD3 | |
| SCHEMBL24611385 | 0.81 | OPRM1 (0.54) | OPRM1OPRL1OPRD1OPRK1DRD3 | |
| SCHEMBL15043695 | 0.79 | OPRM1 (0.58) | OPRM1OPRL1OPRD1OPRK1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0182872-B1 | A PROCESS FOR THE PREPARATION OF CYCLOBUTENE-SUBSTITUTED AROMATIC HYDROCARBONS | THE DOW CHEMICAL COMPANY (US) | 1989-11-08 | — | — | EP | disclosed |
| EP-0182872-A4 | A PROCESS FOR THE PREPARATION OF CYCLOBUTENE-SUBSTITUTED AROMATIC HYDROCARBONS. | DOW CHEMICAL CO (US) | 1986-08-21 | — | — | EP | disclosed |
| EP-0182872-A1 | A PROCESS FOR THE PREPARATION OF CYCLOBUTENE-SUBSTITUTED AROMATIC HYDROCARBONS. | DOW CHEMICAL CO (US) | 1986-06-04 | — | — | EP | disclosed |
| US-4570011-A | PYROLYSIS OF AN ORTHO ALKYL HALOMETHYL AROMATIC HYDROCARBON IN AN INERT | THE DOW CHEMICAL COMPANY (US) | 1986-02-11 | — | — | US | disclosed |
| WO-1985005355-A1 | A PROCESS FOR THE PREPARATION OF CYCLOBUTENE-SUBSTITUTED AROMATIC HYDROCARBONS | THE DOW CHEMICAL COMPANY (US) | 1985-12-05 | — | — | WO | disclosed |