Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 17/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10614521 | 0.87 | FFAR2 (0.61) | FFAR2MEN1KMT2AADRB2LMNA | |
| SCHEMBL10614514 | 0.87 | FFAR2 (0.61) | FFAR2MEN1KMT2AADRB2LMNA | |
| SCHEMBL9862938 | 0.85 | FFAR2 (0.59) | FFAR2MEN1KMT2AADRB2LMNA | |
| SCHEMBL11400312 | 0.85 | FFAR2 (0.59) | FFAR2MEN1KMT2AADRB2LMNA | |
| SCHEMBL2423106 | 0.85 | FFAR2 (0.64) | FFAR2MEN1KMT2ALMNA | |
| SCHEMBL23027132 | 0.82 | FFAR2 (0.56) | FFAR2MEN1KMT2ALMNA | |
| SCHEMBL10867395 | 0.82 | FFAR2 (0.56) | FFAR2MEN1KMT2ALMNA | |
| SCHEMBL11062117 | 0.82 | FFAR2 (0.56) | FFAR2MEN1KMT2ALMNA | |
| SCHEMBL1677147 | 0.81 | FFAR2 (0.62) | FFAR2MEN1KMT2AADRB2LMNA | |
| SCHEMBL1677071 | 0.81 | FFAR2 (0.62) | FFAR2MEN1KMT2AADRB2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0163094-B1 | PREPARATION OF OPTICALLY-ACTIVE ALPHA-SUBSTITUTED PHENYLACETIC ACIDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-08-02 | — | — | EP | disclosed |
| EP-0163094-A2 | Preparation of optically-active alpha-substituted phenylacetic acids | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-12-04 | — | — | EP | disclosed |