Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28992371 | 0.83 | TDP1 (0.56) | TDP1KMT2ASLC6A2SLC6A3LMNA | |
| SCHEMBL29853739 | 0.79 | TDP1 (0.66) | TDP1KMT2ASLC6A2SLC6A3LMNA | |
| SCHEMBL4645175 | 0.79 | TDP1 (0.66) | TDP1KMT2ASLC6A2SLC6A3LMNA | |
| SCHEMBL10611790 | 0.79 | KMT2A (0.56) | TDP1KMT2ASLC6A2SLC6A3LMNA | |
| SCHEMBL336833 | 0.76 | PPARG (0.63) | TDP1KMT2ASLC6A2SLC6A3LMNA | |
| SCHEMBL28758281 | 0.76 | TDP1 (0.61) | TDP1KMT2ASLC6A2SLC6A3LMNA | |
| SCHEMBL29074347 | 0.76 | HSP90AA1 (0.61) | TDP1KMT2ASLC6A2SLC6A3LMNA | |
| SCHEMBL4648309 | 0.76 | TDP1 (0.56) | TDP1KMT2ASLC6A2SLC6A3LMNA | |
| SCHEMBL29083309 | 0.76 | TDP1 (0.56) | TDP1KMT2ASLC6A2SLC6A3LMNA | |
| Benzyl Benzoate SCHEMBL8010992 | 0.75 | KMT2A (1.00) | TDP1KMT2ASLC6A2SLC6A3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4742041-A | DYE PRECURSOR, PROTECTIVE COATING | FUJI PHOTO FILM CO., LTD. (JP) | 1988-05-03 | — | — | US | disclosed |
| US-4251640-A | OF AN UNSATURATED POLYESTER CONTAINING A PEROXIDE INITIATOR AND A PROMOTER | AKZONA INCORPORATED (US) | 1981-02-17 | — | — | US | disclosed |