Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.59 |
| ▸ | JAK2 | O60674 | 1/20 | 0.59 |
| ▸ | ABL1 | P00519 | 1/20 | 0.59 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.59 |
| ▸ | LCK | P06239 | 1/20 | 0.59 |
| ▸ | FYN | P06241 | 1/20 | 0.59 |
| ▸ | CSF1R | P07333 | 1/20 | 0.59 |
| ▸ | RET | P07949 | 1/20 | 0.59 |
| ▸ | IGF1R | P08069 | 1/20 | 0.59 |
| ▸ | MET | P08581 | 1/20 | 0.59 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.59 |
| ▸ | PIM1 | P11309 | 1/20 | 0.59 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.59 |
| ▸ | PRKACA | P17612 | 1/20 | 0.59 |
| ▸ | KDR | P35968 | 1/20 | 0.59 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.59 |
| ▸ | CDK8 | P49336 | 1/20 | 0.59 |
| ▸ | GSK3A | P49840 | 1/20 | 0.59 |
| ▸ | GSK3B | P49841 | 1/20 | 0.59 |
| ▸ | CDK7 | P50613 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL250112 | 0.84 | AURKA (0.63) | AURKAJAK2ABL1NTRK1LCK | |
| SCHEMBL4770511 | 0.82 | AURKA (0.61) | AURKAJAK2ABL1NTRK1LCK | |
| SCHEMBL30075113 | 0.82 | AURKA (0.61) | AURKAJAK2ABL1NTRK1LCK | |
| SCHEMBL6028990 | 0.81 | AURKA (0.59) | AURKAJAK2ABL1NTRK1LCK | |
| SCHEMBL34472005 | 0.81 | AURKA (0.59) | AURKAJAK2ABL1NTRK1LCK | |
| SCHEMBL4770509 | 0.81 | AURKA (0.59) | AURKAJAK2ABL1NTRK1LCK | |
| SCHEMBL18298073 | 0.79 | AURKA (0.68) | AURKAJAK2ABL1NTRK1LCK | |
| Zinc Ion SCHEMBL10622457 | 0.79 | AURKA (0.58) | AURKAJAK2ABL1NTRK1LCK | |
| SCHEMBL11800918 | 0.78 | AURKA (0.56) | AURKAJAK2ABL1NTRK1LCK | |
| SCHEMBL5067749 | 0.77 | AURKA (0.59) | AURKAJAK2ABL1NTRK1LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0218511-B1 | BINDER-CHARGE BONDING AGENT AND PROPELLANT COMPOSITION CONTAINING IT | SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) | 1989-09-06 | — | — | EP | disclosed |