Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | ACP1 | P24666 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | ACACA | Q13085 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.44 |
| ▸ | HTR3B | O95264 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10610967 | 0.85 | SMN1; SMN2 (0.56) | ALDH1A1POLBLMNASMN1; SMN2HPGD | |
| SCHEMBL10613436 | 0.84 | HPGD (0.47) | ALDH1A1LMNASMN1; SMN2HPGDACP1 | |
| Hydrochloric Acid SCHEMBL10612190 | 0.83 | HPGD (0.46) | ALDH1A1LMNASMN1; SMN2HPGDACP1 | |
| SCHEMBL10610777 | 0.82 | MEN1 (0.56) | ALDH1A1LMNASMN1; SMN2HPGDACP1 | |
| SCHEMBL10613503 | 0.81 | SMN1; SMN2 (0.51) | ALDH1A1LMNASMN1; SMN2HPGDACP1 | |
| SCHEMBL10610594 | 0.81 | TSHR (0.52) | ALDH1A1LMNASMN1; SMN2HPGDACP1 | |
| SCHEMBL10611075 | 0.81 | KDM4E (0.58) | ALDH1A1POLBLMNASMN1; SMN2HPGD | |
| SCHEMBL10609061 | 0.80 | SMN1; SMN2 (0.54) | ALDH1A1LMNASMN1; SMN2HPGDMEN1 | |
| SCHEMBL10613512 | 0.79 | SMN1; SMN2 (0.49) | ALDH1A1LMNASMN1; SMN2HPGDACP1 | |
| SCHEMBL10610248 | 0.78 | ACACA (0.67) | ALDH1A1LMNASMN1; SMN2HPGDACP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4728647-A | Amides derived from quinoline, and anxiolytic compositions containing them | RHONE-POULENC SANTE (FR) | 1988-03-01 | — | — | US | claimed |
| US-4728647-A | Amides derived from quinoline, and anxiolytic compositions containing them | RHONE-POULENC SANTE (FR) | 1988-03-01 | — | — | US | disclosed |