Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 9/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10611975 | 0.86 | HMGCR (0.54) | HMGCR | |
| SCHEMBL9726876 | 0.84 | HMGCR (0.58) | HMGCRESR1CHRM1TBXA2RPDE4A | |
| SCHEMBL9726873 | 0.84 | HMGCR (0.58) | HMGCRESR1CHRM1TBXA2RPDE4A | |
| SCHEMBL9726710 | 0.84 | HMGCR (0.39) | HMGCR | |
| SCHEMBL9726719 | 0.84 | HMGCR (0.39) | HMGCR | |
| SCHEMBL9726644 | 0.83 | HMGCR (0.59) | HMGCR | |
| SCHEMBL9726648 | 0.83 | HMGCR (0.59) | HMGCR | |
| SCHEMBL10611764 | 0.82 | HMGCR (0.54) | HMGCR | |
| SCHEMBL10611915 | 0.81 | HMGCR (0.57) | HMGCR | |
| SCHEMBL9798947 | 0.80 | HMGCR (0.36) | HMGCRESR1CHRM1TBXA2RPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1988006584-A1 | ANTIHYPERCHOLESTEROLEMIC TETRAZOLE COMPOUNDS | BRISTOL-MYERS COMPANY (US) | 1988-09-07 | — | — | WO | disclosed |