Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SLC13A5 | Q86YT5 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HMGCR | P04035 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5576846 | 0.76 | CYP19A1 (0.47) | CYP19A1CYP1A2CYP3A4MEN1KMT2A | |
| SCHEMBL987164 | 0.76 | ALDH1A1 (0.44) | ALDH1A1KDM4ELMNATSHRMAPT | |
| Citric Acid SCHEMBL27835074 | 0.75 | ALDH1A1 (0.83) | ALDH1A1KDM4ELMNATSHRMAPT | |
| SCHEMBL26939214 | 0.74 | CYP19A1 (0.49) | ALDH1A1CYP19A1LMNATSHRCYP1A2 | |
| Citric Acid SCHEMBL28058231 | 0.73 | ALDH1A1 (0.71) | ALDH1A1KDM4ELMNATSHRMAPT | |
| Citric Acid SCHEMBL6731419 | 0.73 | ALDH1A1 (0.79) | ALDH1A1KDM4ELMNATSHRMAPT | |
| Citric Acid SCHEMBL28991913 | 0.73 | ALDH1A1 (0.79) | ALDH1A1KDM4ELMNATSHRMAPT | |
| SCHEMBL25397837 | 0.73 | CYP19A1 (0.47) | ALDH1A1CYP19A1LMNATSHRCYP1A2 | |
| Citric Acid SCHEMBL28865923 | 0.73 | ALDH1A1 (0.58) | ALDH1A1KDM4ELMNATSHRMAPT | |
| Citric Acid SCHEMBL11529330 | 0.73 | ALDH1A1 (0.58) | ALDH1A1KDM4ELMNATSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0195047-A4 | AMINOMALONYL ALANINE COMPOUNDS AND USE AS DIETARY SWEETENERS. | RES TRIANGLE INST (US) | 1988-05-31 | — | — | EP | disclosed |
| EP-0195047-A1 | AMINOMALONYL ALANINE COMPOUNDS AND USE AS DIETARY SWEETENERS | RESEARCH TRIANGLE INSTITUTE (US) | 1986-09-24 | — | — | EP | disclosed |
| WO-1986001690-A1 | AMINOMALONYL ALANINE COMPOUNDS AND USE AS DIETARY SWEETENERS | RESEARCH TRIANGLE INSTITUTE (US) | 1986-03-27 | — | — | WO | disclosed |