⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL6813087 | 0.95 | ADH1B (0.48) | — | |
| SCHEMBL2543289 | 0.83 | — | — | |
| SCHEMBL4363952 | 0.81 | — | — | |
| SCHEMBL7167275 | 0.79 | EPHX1 (0.62) | — | |
| SCHEMBL29206062 | 0.79 | EPHX1 (0.62) | — | |
| SCHEMBL7168261 | 0.79 | EPHX1 (0.62) | — | |
| SCHEMBL7168980 | 0.79 | EPHX1 (0.62) | — | |
| SCHEMBL2916614 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL28163908 | 0.72 | ADH1B (0.37) | — | |
| SCHEMBL11132025 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111303070-A | Thiazolinone heterocyclic compounds, process for preparation thereof and pharmaceutical composition comprising the same | 中国科学技术大学 | 2020-06-19 | — | — | CN | claimed |
| CN-109111408-B | Thiazolinone heterocyclic compound, preparation method thereof, medicinal composition and application | 中国科学技术大学 | 2021-03-09 | — | — | CN | disclosed |
| US-10870661-B2 | Nitrogen-containing tricyclic derivatives having HIV replication inhibitory activity | SHIONOGI & CO., LTD. (JP) | 2020-12-22 | — | — | US | disclosed |
| CN-111303070-A | Thiazolinone heterocyclic compounds, process for preparation thereof and pharmaceutical composition comprising the same | 中国科学技术大学 | 2020-06-19 | — | — | CN | disclosed |
| CN-107151250-B | Pyrimidine seven-membered ring compound, preparation method thereof, medicinal composition and application thereof | 安徽省新星药物开发有限责任公司 | 2020-03-27 | — | — | CN | disclosed |
| US-20200055873-A1 | NITROGEN-CONTAINING TRICYCLIC DERIVATIVES HAVING HIV REPLICATION INHIBITORY ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2020-02-20 | — | — | US | disclosed |
| US-20180162876-A1 | NITROGEN-CONTAINING TRICYCLIC DERIVATIVES HAVING HIV REPLICATION INHIBITORY ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2018-06-14 | — | — | US | disclosed |
| US-9975906-B2 | Tricyclic heterocycle derivatives having HIV replication inhibitory effect | SHIONOGI & CO., LTD. (JP) | 2018-05-22 | — | — | US | disclosed |
| EP-3305789-A1 | NITROGEN-CONTAINING TRICYCLIC DERIVATIVE HAVING HIV REPLICATION INHIBITORY ACTIVITY | Shionogi & Co., Ltd. (JP) | 2018-04-11 | — | — | EP | disclosed |
| US-20170253607-A1 | LONG-ACTING HIV PROTEASE INHIBITOR | SHIONOGI & CO., LTD. (JP) | 2017-09-07 | — | — | US | disclosed |
| US-20080085482-A1 | COPOLYMER AND PHOTOTHERMOGRAPHIC MATERIAL CONTAINING THE SAME | KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) | 2008-04-10 | — | — | US | disclosed |
| EP-1909139-A1 | Copolymer and photothermographic material containing the same | Konica Minolta Medical & Graphic, Inc. (JP) | 2008-04-09 | — | — | EP | disclosed |
| EP-1887416-A1 | ELECTROCHROMIC DISPLAY ELEMENT AND FULL-COLOR ELECTROCHROMIC DISPLAY ELEMENT | KONICA MINOLTA HOLDINGS, INC. (JP) | 2008-02-13 | — | — | EP | disclosed |
| US-7262001-B2 | Heat-developable photosensitive material and an image forming method | KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) | 2007-08-28 | — | — | US | disclosed |
| US-20070049620-A1 | Cyclic tertiary amine compound | SANKYO COMPANY, LIMITED (JP) | 2007-03-01 | — | — | US | disclosed |
| EP-1632488-A1 | CYCLIC TERTIARY AMINE COMPOUND | Sankyo Company, Limited (JP) | 2006-03-08 | — | — | EP | disclosed |
| US-20050170298-A1 | Heat-developable photosensitive material and an image forming method | KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) | 2005-08-04 | — | — | US | disclosed |
| US-6080743-A | AS CHEMICAL INTERMEIDATES FOR PREPARING DRUGS | NOVARTIS AG (CH) | 2000-06-27 | — | — | US | disclosed |
| EP-0853617-A1 | NOVEL 2,3-DIOXO-1,2,3,4-TETRAHYDRO-QUINOYXALINYL DERIVATIVES | Novartis AG (CH) | 1998-07-22 | — | — | EP | disclosed |
| WO-1997008155-A1 | NOVEL 2,3-DIOXO-1,2,3,4-TETRAHYDRO-QUINOYXALINYL DERIVATIVES | NOVARTIS AG (CH) | 1997-03-06 | — | — | WO | disclosed |