Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 5/20 | 0.51 |
| ▸ | THRA | P10827 | 4/20 | 0.51 |
| ▸ | PPARG | P37231 | 4/20 | 0.51 |
| ▸ | RXRA | P19793 | 3/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.51 |
| ▸ | ITGAV | P06756 | 1/20 | 0.51 |
| ▸ | PCNA | P12004 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | TTR | P02766 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | PGR | P06401 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10609147 | 0.80 | PCNA (0.55) | THRBTHRAPPARGRXRAPCNA | |
| SCHEMBL1525946 | 0.70 | THRB (0.73) | THRBTHRAPPARGRXRAITGB3 | |
| SCHEMBL13949709 | 0.69 | THRB (0.77) | THRBTHRAPPARGRXRAITGB3 | |
| Tetrac SCHEMBL365951 | 0.69 | THRB (1.00) | THRBTHRAPPARGRXRAITGB3 | |
| SCHEMBL15014468 | 0.68 | KDM4E (0.55) | MEN1KMT2AHSD17B10CYP1A2CYP2C9 | |
| SCHEMBL12781709 | 0.68 | GAA (0.74) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL16610099 | 0.68 | EGLN3 (0.58) | LMNAHSD17B10CYP1A2CYP2C9ALDH1A1 | |
| SCHEMBL1526151 | 0.67 | THRB (0.60) | THRBTHRAPPARGRXRAITGB3 | |
| SCHEMBL16124442 | 0.66 | PCNA (0.69) | THRBTHRAPPARGRXRAPCNA | |
| SCHEMBL9236717 | 0.66 | QPCT (0.57) | HSD17B10CYP1A2ALDH1A1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4741897-A | Thyroxine analogs and reagents for thyroid hormone assays | BAXTER TRAVENOL (US) | 1988-05-03 | — | — | US | disclosed |