SCHEMBL10614331

SCHEMBL10614331

CC(C)(C)N1CC(c2ccc(N)cc2)OC1=O

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FADS1 O60427 8/20 0.41
CYP19A1 P11511 3/20 0.36
HTR2B P41595 1/20 0.36
GRM2 Q14416 1/20 0.35
DDB1 Q16531 2/20 0.33
CRBN Q96SW2 2/20 0.33
CA2 P00918 1/20 0.33
HTR6 P50406 1/20 0.33
HSD11B1 P28845 2/20 0.32
ROCK2 O75116 1/20 0.32
ROCK1 Q13464 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15743660 0.86 MAOB (0.40) FADS1HTR2BDDB1CRBNHSD11B1
SCHEMBL13547510 0.84 FADS1 (0.55) FADS1HTR2BGRM2
SCHEMBL13547508 0.84 FADS1 (0.55) FADS1HTR2BGRM2
SCHEMBL14733319 0.84 FADS1 (0.47) FADS1CYP19A1HTR2BDDB1CRBN
SCHEMBL13395502 0.84 FADS1 (0.47) FADS1CYP19A1HTR2BDDB1CRBN
SCHEMBL13395499 0.84 FADS1 (0.47) FADS1CYP19A1HTR2BDDB1CRBN
SCHEMBL13395496 0.83 FADS1 (0.40) FADS1HTR2BGRM2
SCHEMBL13394528 0.83 HTR2B (0.37) FADS1HTR2BGRM2DDB1CRBN
SCHEMBL10616293 0.78 FADS1 (0.35) FADS1HTR2BCA2HTR6HSD11B1
SCHEMBL11286587 0.76 HTR2B (0.40) FADS1HTR2BGRM2CA2HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4754047-A ANIMAL GROWTH REGULATORS AMERICAN CYANAMID COMPANY (US) 1988-06-28 US disclosed
US-4522822-A Phenylethane derivatives and acid addition salts thereof for increasing lean meat deposition and/or improving lean meat to fat ratio in warm blooded animals AMERICAN CYANAMID COMPANY (US) 1985-06-11 US disclosed
US-4501751-A Phenylethanolamine derivatives and acid addition salts thereof for enhancing the growth rate of meat-producing animals and improving the efficiency of feed utilization thereby AMERICAN CYANAMID COMPANY (US) 1985-02-26 US disclosed
US-4407819-A ANIMAL GROWTH REGULATORS AMERICAN CYANAMID COMPANY (US) 1983-10-04 US disclosed
US-4404222-A Phenylethanolamine derivatives and acid addition salts thereof for enhancing the growth rate of meat-producing animals and improving the efficiency of feed utilization thereby AMERICAN CYANAMID COMPANY (US) 1983-09-13 US disclosed
EP-0049728-A2 Method for enhancing the growth rate of meat-producing animals and for improving the lean meat to fat ratio thereof AMERICAN CYANAMID COMPANY (US) 1982-04-21 EP disclosed