SCHEMBL10614802

SCHEMBL10614802

CCN(C)Cc1ccccc1OC(=O)N(C)C

nearest known ligand 0.72

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.72
NCEH1 Q6PIU2 8/20 0.47
ALDH1A1 P00352 1/20 0.47
PKM P14618 1/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
BCHE P06276 1/20 0.42
LMNA P02545 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10615666 0.88 TSHR (0.68) TSHRNCEH1ALDH1A1PKMBCHE
Hydrochloric Acid SCHEMBL29501016 0.86 TSHR (0.66) TSHRNCEH1ALDH1A1PKMNPC1
SCHEMBL10778554 0.85 TSHR (0.68) TSHRNCEH1ALDH1A1PKMNPC1
SCHEMBL10617746 0.81 ACHE (0.61) TSHRBCHE
SCHEMBL2198922 0.80 TSHR (0.61) TSHRNCEH1ALDH1A1PKMNPC1
Bromomethane SCHEMBL10614793 0.79 ACHE (0.59) TSHRBCHE
Bromomethane SCHEMBL10614766 0.79 ACHE (0.59) TSHRBCHE
Bromomethane SCHEMBL10617745 0.79 ACHE (0.59) TSHRBCHE
Bromomethane SCHEMBL10614806 0.79 ACHE (0.59) TSHRBCHE
Bromomethane SCHEMBL10617778 0.79 ACHE (0.59) TSHRBCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-H443-H CHEMICAL WARFARE THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 1988-03-01 US disclosed