Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5013975 | 0.86 | NOS1 (0.61) | NOS1DHFR | |
| SCHEMBL10850465 | 0.84 | NOS1 (0.71) | NOS1DHFR | |
| SCHEMBL8813993 | 0.83 | NOS1 (0.61) | NOS1DHFR | |
| SCHEMBL10852865 | 0.83 | NOS1 (0.82) | NOS1DHFR | |
| SCHEMBL10848710 | 0.83 | NOS1 (0.58) | NOS1DHFR | |
| SCHEMBL6251731 | 0.81 | NOS1 (0.55) | NOS1DHFR | |
| SCHEMBL14435374 | 0.81 | NOS1 (0.55) | NOS1DHFR | |
| SCHEMBL30432658 | 0.81 | NOS1 (0.55) | NOS1DHFR | |
| SCHEMBL26500537 | 0.80 | NOS1 (0.62) | NOS1DHFR | |
| SCHEMBL14075489 | 0.80 | NOS1 (0.54) | NOS1DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0108890-B1 | PHARMACEUTICALLY ACTIVE PTERIDINE DERIVATIVES | THE WELLCOME FOUNDATION LIMITED (GB) | 1988-12-07 | — | — | EP | disclosed |
| US-4701455-A | NERVOUS SYSTEM DISORDERS, PARKINSON'S DISEASE | BURROUGHS WELLCOME CO. (US) | 1987-10-20 | — | — | US | disclosed |
| US-4587340-A | ANTIDEPRESSANTS | BURROUGHS WELLCOME CO. (US) | 1986-05-06 | — | — | US | disclosed |
| EP-0108890-A2 | Pharmaceutically active pteridine derivatives | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-05-23 | — | — | EP | disclosed |
| US-4079056-A | REACTING 2,4-DIAMINO-6-PTERIDINE-METHANOL-HBR WITH TRIPHENYLPHOSPHINE DIBROMIDE OR PHOSPHORUS TRIBROMIDE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH, EDUCATION AND WELFARE (US) | 1978-03-14 | — | — | US | disclosed |
| US-4077957-A | INTERMEDIATE FOR METHOTREXATE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH, EDUCATION AND WELFARE (US) | 1978-03-07 | — | — | US | disclosed |