Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 8/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PAH | P00439 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10615690 | 0.76 | KDM4E (0.43) | NOS1NOS3NOS2USP2CASP7 | |
| Hydrochloric Acid SCHEMBL10798525 | 0.74 | KDM4E (0.42) | NOS1NOS3NOS2USP2CASP7 | |
| Hydrochloric Acid SCHEMBL10803149 | 0.71 | PAH (0.42) | NOS1NOS3NOS2USP2CASP7 | |
| SCHEMBL25592958 | 0.70 | NOS1 (0.50) | NOS1NOS3NOS2USP2CASP7 | |
| SCHEMBL156195 | 0.70 | KDM4E (0.57) | NOS1NOS3NOS2USP2CASP7 | |
| Hydrochloric Acid SCHEMBL10618526 | 0.69 | NOS1 (0.42) | NOS1NOS3NOS2USP2CASP7 | |
| Hydrochloric Acid SCHEMBL10799983 | 0.69 | KDM4E (0.51) | NOS1NOS3NOS2USP2CASP7 | |
| Hydrochloric Acid SCHEMBL10799994 | 0.69 | KDM4E (0.51) | NOS1NOS3NOS2USP2CASP7 | |
| Hydrochloric Acid SCHEMBL10618047 | 0.69 | KDM4E (0.47) | NOS1NOS3NOS2USP2CASP7 | |
| Hydrochloric Acid SCHEMBL10616936 | 0.68 | NOS1 (0.41) | NOS1NOS3NOS2USP2CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0108890-B1 | PHARMACEUTICALLY ACTIVE PTERIDINE DERIVATIVES | THE WELLCOME FOUNDATION LIMITED (GB) | 1988-12-07 | — | — | EP | disclosed |
| US-4665182-A | Biopterin analogs | BURROUGHS WELLCOME CO. (US) | 1987-05-12 | — | — | US | disclosed |
| EP-0108890-A2 | Pharmaceutically active pteridine derivatives | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-05-23 | — | — | EP | disclosed |