SCHEMBL10616379

SCHEMBL10616379

O=c1ccc(N=Nc2ccccc2)ccc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 1.00
KMT2A Q03164 5/20 1.00
MAPT P10636 5/20 1.00
MAPK1 P28482 2/20 1.00
TDP1 Q9NUW8 2/20 1.00
KDM4E B2RXH2 1/20 1.00
HSP90AA1 P07900 1/20 1.00
NPC1 O15118 3/20 0.58
MMP2 P08253 1/20 0.56
DBH P09172 1/20 0.56
ALDH1A1 P00352 2/20 0.52
TRPA1 O75762 1/20 0.52
CYP2D6 P10635 2/20 0.48
POLB P06746 1/20 0.48
CASP3 P42574 2/20 0.47
SENP7 Q9BQF6 2/20 0.47
SENP6 Q9GZR1 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
THRB P10828 1/20 0.47
FTO Q9C0B1 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11698720 0.76 MEN1 (0.61) MEN1KMT2AMAPTMAPK1TDP1
SCHEMBL11698723 0.76 MEN1 (0.61) MEN1KMT2AMAPTMAPK1TDP1
SCHEMBL13277532 0.75 ALDH1A1 (0.92) MEN1KMT2AMAPTMAPK1TDP1
SCHEMBL21023910 0.75 ALDH1A1 (0.92) MEN1KMT2AMAPTMAPK1TDP1
SCHEMBL90893 0.75 ALDH1A1 (0.92) MEN1KMT2AMAPTMAPK1TDP1
SCHEMBL2239365 0.75 ALDH1A1 (0.92) MEN1KMT2AMAPTMAPK1TDP1
SCHEMBL9418780 0.75 ALDH1A1 (0.92) MEN1KMT2AMAPTMAPK1TDP1
SCHEMBL21024214 0.75 ALDH1A1 (0.92) MEN1KMT2AMAPTMAPK1TDP1
Azobenzene SCHEMBL182577 0.75 ALDH1A1 (0.92) MEN1KMT2AMAPTMAPK1TDP1
Azobenzene SCHEMBL182578 0.75 ALDH1A1 (0.92) MEN1KMT2AMAPTMAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-63291443-A None JP disclosed
JP-S63291443-A MANUFACTURE OF SEMICONDUCTOR DEVICE HITACHI LTD 1988-11-29 JP disclosed