Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.65 |
| ▸ | HPGD | P15428 | 4/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10615355 | 0.83 | KDM4E (0.44) | KDM4EALDH1A1HPGDTSHRPOLB | |
| SCHEMBL10762340 | 0.79 | KDM4E (0.65) | KDM4EALDH1A1HPGDGAATSHR | |
| SCHEMBL3528800 | 0.79 | ALDH1A1 (1.00) | KDM4EALDH1A1HPGDGAATSHR | |
| SCHEMBL10761937 | 0.78 | CHRM3 (0.46) | HPGDTSHRMAPTHSD17B10HTR1A | |
| Hydrochloric Acid SCHEMBL10767066 | 0.78 | KDM4E (0.63) | KDM4EALDH1A1HPGDGAATSHR | |
| Hydrochloric Acid SCHEMBL10615404 | 0.77 | CHRM3 (0.45) | HPGDTSHRMAPTHSD17B10HTR1A | |
| SCHEMBL10615480 | 0.76 | HTR2A (0.42) | HTR1AHTR7 | |
| SCHEMBL10615435 | 0.75 | HTR2A (0.43) | HTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL10618254 | 0.74 | HTR2A (0.46) | HTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL10617650 | 0.74 | HTR2A (0.46) | HTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0288477-A1 | 2,3-DIHYDRO-1H-PHENALENE-2-AMINO COMPOUNDS AS ANTI-PSYCHOTIC DRUGS | THE UPJOHN COMPANY (US) | 1988-11-02 | — | — | EP | claimed |
| EP-0234113-A1 | 2,3-Dihydro-1H-phenalene-2-amino compounds as anti-psychotic drugs | THE UPJOHN COMPANY (US) | 1987-09-02 | — | — | EP | claimed |
| WO-1987004153-A1 | 2,3-DIHYDRO-1H-PHENALENE-2-AMINO COMPOUNDS AS ANTI-PSYCHOTIC DRUGS | THE UPJOHN COMPANY (US) | 1987-07-16 | — | — | WO | claimed |
| EP-0288477-A1 | 2,3-DIHYDRO-1H-PHENALENE-2-AMINO COMPOUNDS AS ANTI-PSYCHOTIC DRUGS | THE UPJOHN COMPANY (US) | 1988-11-02 | — | — | EP | disclosed |
| EP-0234113-A1 | 2,3-Dihydro-1H-phenalene-2-amino compounds as anti-psychotic drugs | THE UPJOHN COMPANY (US) | 1987-09-02 | — | — | EP | disclosed |
| WO-1987004153-A1 | 2,3-DIHYDRO-1H-PHENALENE-2-AMINO COMPOUNDS AS ANTI-PSYCHOTIC DRUGS | THE UPJOHN COMPANY (US) | 1987-07-16 | — | — | WO | disclosed |