SCHEMBL10617

SCHEMBL10617

O=c1[nH]c2ccccc2cc1F

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DAO P14920 3/20 0.60
DDO Q99489 2/20 0.60
BRD4 O60885 1/20 0.60
KDR P35968 2/20 0.56
CHEK1 O14757 1/20 0.56
GRIN2D O15399 2/20 0.54
GRIN3B O60391 2/20 0.54
GRIN1 Q05586 2/20 0.54
GRIN2A Q12879 2/20 0.54
GRIN2B Q13224 2/20 0.54
GRIN2C Q14957 2/20 0.54
GRIN3A Q8TCU5 2/20 0.54
KDM4E B2RXH2 5/20 0.50
PDGFRB P09619 1/20 0.49
FGFR1 P11362 1/20 0.49
FLT3 P36888 2/20 0.47
CYP2A6 P11509 1/20 0.47
AOC3 Q16853 2/20 0.47
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29370120 1.00 DAO (0.60) DAODDOBRD4KDRCHEK1
Hydrochloric Acid SCHEMBL6506378 0.98 DAO (0.58) DAODDOBRD4KDRCHEK1
SCHEMBL27818462 0.98 DAO (0.58) DAODDOBRD4KDRCHEK1
Formaldehyde SCHEMBL28001667 0.96 DAO (0.56) DAODDOBRD4KDRCHEK1
Formic Acid SCHEMBL3896017 0.91 DAO (0.56) DAODDOBRD4KDRCHEK1
SCHEMBL28589648 0.91 KDR (0.53) DAODDOBRD4KDRCHEK1
Pyrrole SCHEMBL28035663 0.91 BRD4 (0.51) DAODDOBRD4KDRCHEK1
Azetidine SCHEMBL8198613 0.91 DAO (0.51) DAODDOBRD4KDRCHEK1
Sulfuric Acid SCHEMBL29126778 0.89 BRD4 (0.50) DAODDOBRD4KDRCHEK1
SCHEMBL28439712 0.89 CA12 (0.67) DAODDOBRD4KDRCHEK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 40147 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4746896-A1 TREATMENT OF STAPHYLOCOCCAL ABSCESSES Katholieke Universiteit Leuven (BE) 2026-05-27 EP claimed
CN-122079862-A Natural product 3-methyl carbazole derivative and preparation method and application thereof 2026-05-26 CN claimed
CN-122080347-A Double-hole cation covalent organic framework material, preparation method thereof, ratio fluorescent probe and application 2026-05-26 CN claimed
CN-122079888-A Marbofloxacin intermediate 2026-05-26 CN claimed
EP-4743153-A1 MEDICAL SYSTEMS FOR TREATING CONDITIONS AND DISEASES OF THE PATIENT'S BODY CAVITIES UTT Urine Topical Treatment Ltd (IL) 2026-05-20 EP claimed
EP-4743122-A1 THERAPEUTIC SEALANTS BASED UPON DRUG CONJUGATES The Johns Hopkins University (US) 2026-05-20 EP claimed
CN-115215923-B Macrocyclic broad-spectrum antibiotics 豪夫迈·罗氏有限公司 2026-05-19 CN claimed
CN-122055161-A Microbiota Restoration Therapy (MRT) compositions and methods of administration 辉凌微生物组有限公司 2026-05-15 CN claimed
CN-122032507-A Preparation method of zein modified sodium alginate aerogel adsorbent and application of zein modified sodium alginate aerogel adsorbent in antibiotic adsorption 中国科学院兰州化学物理研究所 2026-05-15 CN claimed
EP-4739326-A2 PRODUCTION & SECRETION OF AUXIN-LIKE MOLECULES IN BACTERIA SNIPR Biome ApS (DK) 2026-05-13 EP claimed
US-5328954-A Bactericides in coatings for medical devices of polyurethanes linked with aminopolycarboxylic acid ICET, INC. (US) 1994-07-12 US claimed
EP-0595890-A1 ANTIMICROBIAL TREATMENT METHODS AND COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1994-05-11 EP claimed
EP-0437128-B1 Use of derivatives of fluoroquinolone in the treatment of pneumocystis carinii pneumonia RHONE POULENC SANTE (FR) 1994-02-16 EP claimed
WO-1993001818-A1 ANTIMICROBIAL TREATMENT METHODS AND COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1993-02-04 WO claimed
US-5179096-A Treatment or pneumocystosis pneumonia RHONE-POULENC SANTE (FR) 1993-01-12 US claimed
EP-0469021-A1 DETERMINATION OF FACTORS AFFECTING GENE REGULATION AND/OR GENE REPLICATION. BIO ORBIT OY (FI) 1992-02-05 EP claimed
EP-0456724-A1 COMPOSITION AND METHOD FOR TREATING BENIGN PROSTATIC HYPERTROPHY. IMMUNOLYTICS INC (US) 1991-11-21 EP claimed
EP-0437128-A2 Use of derivatives of fluoroquinolone in the treatment of pneumocystis carinii pneumonia RHONE-POULENC SANTE (FR) 1991-07-17 EP claimed
WO-1990012887-A1 DETERMINATION OF FACTORS AFFECTING GENE REGULATION AND/OR GENE REPLICATION BIO-ORBIT OY (FI) 1990-11-01 WO claimed
WO-1990008555-A1 COMPOSITION AND METHOD FOR TREATING BENIGN PROSTATIC HYPERTROPHY IMMUNOLYTICS, INC. (US) 1990-08-09 WO claimed