Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 4/20 | 0.56 |
| ▸ | DDO | Q99489 | 2/20 | 0.56 |
| ▸ | BRD4 | O60885 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 2/20 | 0.49 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.49 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.46 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.46 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.46 |
| ▸ | FLT3 | P36888 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29370120 | 0.91 | DAO (0.60) | DAODDOBRD4KDRCHEK1 | |
| SCHEMBL10617 | 0.91 | DAO (0.60) | DAODDOBRD4KDRCHEK1 | |
| Hydrochloric Acid SCHEMBL6506378 | 0.89 | DAO (0.58) | DAODDOBRD4KDRCHEK1 | |
| SCHEMBL27818462 | 0.89 | DAO (0.58) | DAODDOBRD4KDRCHEK1 | |
| Formaldehyde SCHEMBL28001667 | 0.87 | DAO (0.56) | DAODDOBRD4KDRCHEK1 | |
| Acetic Acid SCHEMBL28431508 | 0.85 | DAO (0.54) | DAODDOBRD4KDRCHEK1 | |
| SCHEMBL27684263 | 0.83 | BRD4 (0.53) | DAODDOBRD4KDRCHEK1 | |
| SCHEMBL28589648 | 0.83 | KDR (0.53) | DAODDOBRD4KDRCHEK1 | |
| Pyrrole SCHEMBL28035663 | 0.83 | BRD4 (0.51) | DAODDOBRD4KDRCHEK1 | |
| Azetidine SCHEMBL8198613 | 0.83 | DAO (0.51) | DAODDOBRD4KDRCHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100497331-C | 7-(4-oxime-3-amino-1-piperidine) quinoline carboxylic acid derivative and method for making same | BEIJING DOUBLE CRANE PHARMACEU (CN) | 2009-06-10 | — | — | CN | disclosed |
| WO-2009030106-A1 | 7-(4-OXIMINO-3-AMINO-1-PIPERIDYL)QUINOLINECARBOXYLIC ACID DERIVATIVES AND THEIR PREPARATION METHODS | INSTITUTE OF MEDICINAL BIOTECHNOLOGY CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2009-03-12 | — | — | WO | disclosed |
| CN-101117336-A | 7-(4-oxime-3-amino-1-piperidine) quinoline carboxylic acid derivative and method for making same | INST OF MEDICAL BIOTECHNOLOGY (CN) | 2008-02-06 | — | — | CN | disclosed |