Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 8/20 | 0.91 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10618513 | 1.00 | GBA1 (0.91) | GBA1TNFTSHRALDH1A1LMNA | |
| SCHEMBL10619629 | 1.00 | GBA1 (0.91) | GBA1TNFTSHRALDH1A1LMNA | |
| SCHEMBL10621226 | 1.00 | GBA1 (0.91) | GBA1TNFTSHRALDH1A1LMNA | |
| SCHEMBL10618559 | 1.00 | GBA1 (0.91) | GBA1TNFTSHRALDH1A1LMNA | |
| SCHEMBL10616769 | 1.00 | GBA1 (0.91) | GBA1TNFTSHRALDH1A1LMNA | |
| SCHEMBL3649428 | 0.98 | GBA1 (0.96) | GBA1TNFTSHR | |
| SCHEMBL3652751 | 0.95 | GBA1 (0.91) | GBA1TNFTSHR | |
| SCHEMBL17833025 | 0.95 | GBA1 (1.00) | GBA1TNFTSHR | |
| SCHEMBL25627228 | 0.93 | GBA1 (0.87) | GBA1TNFTSHRALDH1A1LMNA | |
| SCHEMBL7750204 | 0.93 | GBA1 (0.95) | GBA1TNFTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0276238-A1 | HEXASUBSTITUTED CYCLOHEXANE COMPOUNDS | MERCK PATENT GmbH (DE) | 1988-08-03 | — | — | EP | disclosed |
| WO-1988000940-A2 | HEXASUBSTITUTED CYCLOHEXANE COMPOUNDS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1988-02-11 | — | — | WO | disclosed |