SCHEMBL25627228

SCHEMBL25627228

CCCCCCCCO[C@H]1[C@H](O)[C@@H](O)[C@H](OCCCCCCCC)[C@@H](O)[C@H]1O

nearest known ligand 0.87

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GBA1 P04062 8/20 0.87
MEN1 O00255 1/20 0.41
THRB P10828 1/20 0.41
HTT P42858 1/20 0.41
KMT2A Q03164 1/20 0.41
MAPT P10636 1/20 0.41
TSHR P16473 1/20 0.41
ALDH1A1 P00352 1/20 0.41
LMNA P02545 1/20 0.41
NR5A1 Q13285 1/20 0.41
TNF P01375 1/20 0.40
LPAR3 Q9UBY5 3/20 0.40
LPAR1 Q92633 2/20 0.40
LPAR2 Q9HBW0 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3651829 0.98 GBA1 (0.91) GBA1TSHRALDH1A1LMNA
SCHEMBL10616804 0.98 GBA1 (0.91) GBA1TSHRALDH1A1LMNA
SCHEMBL9481368 0.95 GBA1 (0.87) GBA1TSHR
SCHEMBL10616769 0.93 GBA1 (0.91) GBA1MEN1THRBHTTKMT2A
SCHEMBL10621226 0.93 GBA1 (0.91) GBA1MEN1THRBHTTKMT2A
SCHEMBL10618513 0.93 GBA1 (0.91) GBA1MEN1THRBHTTKMT2A
SCHEMBL10617470 0.93 GBA1 (0.91) GBA1MEN1THRBHTTKMT2A
SCHEMBL17833025 0.93 GBA1 (1.00) GBA1TSHRTNF
SCHEMBL10618559 0.93 GBA1 (0.91) GBA1MEN1THRBHTTKMT2A
SCHEMBL10619629 0.93 GBA1 (0.91) GBA1MEN1THRBHTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192949-A1 POLYCARBONATE RESIN, POLYCARBONATE RESIN COMPOSITION, OPTICAL MOLDED ARTICLE COMPRISING SAME, AND CYCLIC CARBONATE ASAHI KASEI KABUSHIKI KAISHA (JP) 2023-06-22 US disclosed
US-20230192949-A1 POLYCARBONATE RESIN, POLYCARBONATE RESIN COMPOSITION, OPTICAL MOLDED ARTICLE COMPRISING SAME, AND CYCLIC CARBONATE ASAHI KASEI KABUSHIKI KAISHA (JP) 2023-06-22 US disclosed