Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10617230 | 0.84 | MGAM (0.41) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL10620347 | 0.78 | TSHR (0.44) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL5368137 | 0.74 | LCK (0.51) | TSHRKDM4EALDH1A1HSD17B10ALOX15 | |
| SCHEMBL10596292 | 0.72 | GAA (0.54) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL10617060 | 0.72 | GAA (0.56) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL10617902 | 0.72 | TSHR (0.54) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL10617275 | 0.71 | GAA (0.55) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL10621732 | 0.71 | GAA (0.55) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL10617890 | 0.70 | MGAM (0.40) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL10617365 | 0.69 | GAA (0.58) | GAAMGAMAMY1ASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0285267-A2 | Pyridine derivatives for treatment and prevention of liver damage, and their preparation | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-10-05 | — | — | EP | disclosed |