SCHEMBL10618566

SCHEMBL10618566

Cc1cc(O)c(C(=O)C=Cc2ccccc2)c(=O)o1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 11/20 0.76
KMT2A Q03164 11/20 0.76
USP2 O75604 3/20 0.76
PPARG P37231 2/20 0.76
RAB9A P51151 5/20 0.73
PKM P14618 3/20 0.73
NPC1 O15118 3/20 0.73
MAPT P10636 6/20 0.70
POLB P06746 3/20 0.70
NPSR1 Q6W5P4 3/20 0.70
RECQL P46063 2/20 0.70
KDM4E B2RXH2 2/20 0.66
GAA P10253 1/20 0.65
HTT P42858 1/20 0.65
NR3C1 P04150 1/20 0.65
SMN1; SMN2 Q16637 2/20 0.60
PLIN1 O60240 1/20 0.60
ALOX12 P18054 1/20 0.60
PLIN5 Q00G26 1/20 0.60
ABHD5 Q8WTS1 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10618560 1.00 MEN1 (0.76) MEN1KMT2AUSP2PPARGRAB9A
SCHEMBL5150395 0.89 MEN1 (0.81) MEN1KMT2AUSP2PPARGRAB9A
SCHEMBL5150390 0.89 MEN1 (0.81) MEN1KMT2AUSP2PPARGRAB9A
SCHEMBL5631761 0.88 MAPT (0.73) MEN1KMT2AUSP2PPARGRAB9A
SCHEMBL5631764 0.88 MAPT (0.73) MEN1KMT2AUSP2PPARGRAB9A
SCHEMBL13403219 0.87 MEN1 (0.59) MEN1KMT2AUSP2PPARGRAB9A
SCHEMBL13479658 0.87 MAPT (0.71) MEN1KMT2AUSP2PPARGRAB9A
SCHEMBL28490585 0.86 MEN1 (0.77) MEN1KMT2AUSP2PPARGRAB9A
SCHEMBL26984892 0.86 KMT2A (0.77) MEN1KMT2AUSP2PPARGRAB9A
SCHEMBL28490584 0.86 MEN1 (0.77) MEN1KMT2AUSP2PPARGRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1988009783-A1 POLYMERIC ULTRAVIOLET LIGHT ABSORBERS BIOPOLYMERS LIMITED (AU) 1988-12-15 WO claimed
WO-1988009783-A1 POLYMERIC ULTRAVIOLET LIGHT ABSORBERS BIOPOLYMERS LIMITED (AU) 1988-12-15 WO disclosed