Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 12/20 | 0.77 |
| ▸ | MEN1 | O00255 | 11/20 | 0.77 |
| ▸ | USP2 | O75604 | 3/20 | 0.77 |
| ▸ | RAB9A | P51151 | 5/20 | 0.73 |
| ▸ | PKM | P14618 | 3/20 | 0.73 |
| ▸ | NPC1 | O15118 | 3/20 | 0.73 |
| ▸ | PPARG | P37231 | 2/20 | 0.73 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.69 |
| ▸ | POLB | P06746 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 5/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | RECQL | P46063 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.62 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5150390 | 0.89 | MEN1 (0.81) | KMT2AMEN1USP2RAB9APKM | |
| SCHEMBL5150395 | 0.89 | MEN1 (0.81) | KMT2AMEN1USP2RAB9APKM | |
| SCHEMBL28490585 | 0.87 | MEN1 (0.77) | KMT2AMEN1USP2RAB9APKM | |
| SCHEMBL28490584 | 0.87 | MEN1 (0.77) | KMT2AMEN1USP2RAB9APKM | |
| SCHEMBL10618566 | 0.86 | MEN1 (0.76) | KMT2AMEN1USP2RAB9APKM | |
| SCHEMBL10618560 | 0.86 | MEN1 (0.76) | KMT2AMEN1USP2RAB9APKM | |
| SCHEMBL6416915 | 0.86 | MEN1 (0.75) | KMT2AMEN1USP2RAB9APKM | |
| SCHEMBL6416922 | 0.86 | MEN1 (0.75) | KMT2AMEN1USP2RAB9APKM | |
| SCHEMBL6419030 | 0.85 | MEN1 (0.73) | KMT2AMEN1USP2RAB9APKM | |
| SCHEMBL6419036 | 0.85 | MEN1 (0.73) | KMT2AMEN1USP2RAB9APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250366472-A1 | 1-AMINOCYCLOPROPANE-1-CARBOXYLIC ACID OXIDASE INHIBITORS (ACO-I) | ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE (GB) | 2025-12-04 | — | — | US | claimed |
| EP-4551018-A1 | 1-AMINOCYCLOPROPANE-1-CARBOXYLIC ACID OXIDASE INHIBITORS (ACO-I) | Royal Holloway & Bedford New College (GB) | 2025-05-14 | — | — | EP | claimed |
| WO-2024009078-A1 | 1-AMINOCYCLOPROPANE-1-CARBOXYLIC ACID OXIDASE INHIBITORS (ACO-I) | ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE (GB) | 2024-01-11 | — | — | WO | claimed |
| US-20250366472-A1 | 1-AMINOCYCLOPROPANE-1-CARBOXYLIC ACID OXIDASE INHIBITORS (ACO-I) | ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE (GB) | 2025-12-04 | — | — | US | disclosed |
| EP-4551018-A1 | 1-AMINOCYCLOPROPANE-1-CARBOXYLIC ACID OXIDASE INHIBITORS (ACO-I) | Royal Holloway & Bedford New College (GB) | 2025-05-14 | — | — | EP | disclosed |
| WO-2024009078-A1 | 1-AMINOCYCLOPROPANE-1-CARBOXYLIC ACID OXIDASE INHIBITORS (ACO-I) | ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE (GB) | 2024-01-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250366472-A1 | 1-AMINOCYCLOPROPANE-1-CARBOXYLIC ACID OXIDASE INHIBITORS (ACO-I) | DAO, ACOX1, HAO1 | KMT2A 3817/4885MEN1 3279/4885USP2 717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.