SCHEMBL1061880

SCHEMBL1061880

COc1ccc(Br)cc1S(=O)(=O)NC(=O)C=Cc1cc(Cl)ccc1Cc1ccc2ccccc2c1

nearest known ligand 0.83

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ PTGER3 P43115 16/20 0.83
▸ PTGER4 P35408 5/20 0.83
▸ PTGER1 P34995 3/20 0.83
▸ DRD3 P35462 1/20 0.83
▸ PTGER2 P43116 3/20 0.49
▸ KDM4E B2RXH2 2/20 0.47
▸ MEN1 O00255 1/20 0.47
▸ LMNA P02545 1/20 0.47
▸ MAPT P10636 1/20 0.47
▸ KMT2A Q03164 1/20 0.47
▸ WDR5 P61964 2/20 0.43
▸ MYC P01106 1/20 0.43
▸ TBXA2R P21731 1/20 0.41
▸ PTGFR P43088 1/20 0.41
▸ PTGDR Q13258 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1061876 1.00 PTGER3 (0.83) PTGER3PTGER4PTGER1DRD3PTGER2
SCHEMBL30145373 1.00 PTGER3 (0.83) PTGER3PTGER4PTGER1DRD3PTGER2
SCHEMBL7931390 0.96 PTGER3 (0.76) PTGER3PTGER4PTGER1DRD3PTGER2
SCHEMBL7931387 0.96 PTGER3 (0.76) PTGER3PTGER4PTGER1DRD3PTGER2
SCHEMBL7817274 0.94 PTGER3 (0.83) PTGER3PTGER4PTGER1DRD3PTGER2
SCHEMBL7817269 0.94 PTGER3 (0.83) PTGER3PTGER4PTGER1DRD3PTGER2
SCHEMBL7928545 0.92 PTGER3 (0.70) PTGER3PTGER4PTGER1DRD3PTGER2
SCHEMBL7928549 0.92 PTGER3 (0.70) PTGER3PTGER4PTGER1DRD3PTGER2
SCHEMBL7929856 0.92 PTGER3 (0.86) PTGER3PTGER4PTGER1DRD3PTGER2
SCHEMBL7929853 0.92 PTGER3 (0.86) PTGER3PTGER4PTGER1DRD3PTGER2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110008258-A1 METHODS RELATING TO BREATHING DISORDERS SAMSARA MEDICIN AB (SE) 2011-01-13 — — US claimed
EP-2219736-A2 METHODS RELATING TO BREATHING DISORDERS Samsara Medicin AB (SE) 2010-08-25 — — EP claimed
WO-2009063226-A2 METHODS RELATING TO BREATHING DISORDERS KAROLINSKA INSTITUTET INNOVATIONS AB (SE) 2009-05-22 — — WO claimed
CN-115624626-B Application of EP3 receptor in prevention and treatment of neurogenic bladder after spinal cord injury 山东大学齐鲁医院 2024-04-09 — — CN disclosed
CN-115624626-A Application of EP3 receptor in prevention and treatment of neurogenic bladder after spinal cord injury 山东大学齐鲁医院 2023-01-20 — — CN disclosed
US-20110008258-A1 METHODS RELATING TO BREATHING DISORDERS SAMSARA MEDICIN AB (SE) 2011-01-13 — — US disclosed
EP-2219736-A2 METHODS RELATING TO BREATHING DISORDERS Samsara Medicin AB (SE) 2010-08-25 — — EP disclosed
WO-2009063226-A2 METHODS RELATING TO BREATHING DISORDERS KAROLINSKA INSTITUTET INNOVATIONS AB (SE) 2009-05-22 — — WO disclosed
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