Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 16/20 | 0.83 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.83 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.83 |
| ▸ | DRD3 | P35462 | 1/20 | 0.83 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | WDR5 | P61964 | 2/20 | 0.43 |
| ▸ | MYC | P01106 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | PTGFR | P43088 | 1/20 | 0.41 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.41 |
| ▸ | CPT1A | P50416 | 1/20 | 0.41 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7817269 | 1.00 | PTGER3 (0.83) | PTGER3PTGER4PTGER1DRD3PTGER2 | |
| SCHEMBL1061876 | 0.94 | PTGER3 (0.83) | PTGER3PTGER4PTGER1DRD3PTGER2 | |
| SCHEMBL1061880 | 0.94 | PTGER3 (0.83) | PTGER3PTGER4PTGER1DRD3PTGER2 | |
| SCHEMBL30145373 | 0.94 | PTGER3 (0.83) | PTGER3PTGER4PTGER1DRD3PTGER2 | |
| SCHEMBL29376849 | 0.91 | PTGER3 (1.00) | PTGER3PTGER4PTGER1DRD3PTGER2 | |
| SCHEMBL29988642 | 0.91 | PTGER3 (1.00) | PTGER3PTGER4PTGER1DRD3PTGER2 | |
| SCHEMBL6651935 | 0.91 | PTGER3 (1.00) | PTGER3PTGER4PTGER1DRD3PTGER2 | |
| SCHEMBL6651946 | 0.91 | PTGER3 (1.00) | PTGER3PTGER4PTGER1DRD3PTGER2 | |
| SCHEMBL29663670 | 0.91 | PTGER3 (1.00) | PTGER3PTGER4PTGER1DRD3PTGER2 | |
| SCHEMBL7931390 | 0.89 | PTGER3 (0.76) | PTGER3PTGER4PTGER1DRD3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242493-B1 | PROSTAGLANDIN INHIBITORS; ANALGESICS, ANTIPYRETICS, ANTIINFLAMMATORY AGENTS | MERCK FROSST CANADA & CO. (CA) | 2001-06-05 | — | — | US | disclosed |
| EP-1071648-A2 | CARBOXYLIC ACIDS AND ACYLSULFONAMIDES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT | Merck Frosst Canada & Co. (CA) | 2001-01-31 | — | — | EP | disclosed |
| WO-1999047497-A2 | CARBOXYLIC ACIDS AND ACYLSULFONAMIDES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT | MERCK FROSST CANADA & CO. (CA) | 1999-09-23 | — | — | WO | disclosed |