Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 9/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | SLC18A3 | Q16572 | 3/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10620204 | 1.00 | HCRTR2 (0.37) | HCRTR2IDO1SLC18A3SIGMAR1GRIN2B | |
| SCHEMBL10624141 | 0.87 | PTAFR (0.34) | — | |
| SCHEMBL10624163 | 0.85 | TSHR (0.32) | SLC18A3 | |
| SCHEMBL10619931 | 0.85 | DRD2 (0.37) | IDO1SLC18A3 | |
| SCHEMBL10624169 | 0.85 | TSHR (0.32) | SLC18A3 | |
| SCHEMBL10624537 | 0.85 | DRD2 (0.37) | HCRTR2SLC18A3 | |
| SCHEMBL10621649 | 0.85 | HCRTR2 (0.37) | HCRTR2IDO1SLC18A3SIGMAR1 | |
| SCHEMBL10621654 | 0.85 | HCRTR2 (0.37) | HCRTR2IDO1SLC18A3SIGMAR1 | |
| SCHEMBL10622160 | 0.83 | DRD2 (0.42) | HCRTR2 | |
| SCHEMBL10619565 | 0.83 | SPHK1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4730904-A | Organosilicon compounds | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1988-03-15 | — | — | US | disclosed |