Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 5/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH5A1 | P51649 | 2/20 | 0.33 |
| ▸ | ABAT | P80404 | 2/20 | 0.33 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.33 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.32 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2237311 | 0.82 | ALDH1A1 (0.47) | ALDH1A1HSD17B10TDP1PTGS2KDM4E | |
| SCHEMBL10619177 | 0.82 | ALDH1A1 (0.50) | ALDH1A1HSD17B10TDP1PTGS2KDM4E | |
| SCHEMBL27436316 | 0.82 | ALDH1A1 (0.50) | ALDH1A1HSD17B10TDP1PTGS2KDM4E | |
| SCHEMBL27496098 | 0.82 | ALDH1A1 (0.50) | ALDH1A1HSD17B10TDP1PTGS2KDM4E | |
| SCHEMBL2232812 | 0.82 | ALDH1A1 (0.50) | ALDH1A1HSD17B10TDP1PTGS2KDM4E | |
| SCHEMBL5086097 | 0.82 | ALDH1A1 (0.50) | ALDH1A1HSD17B10TDP1PTGS2KDM4E | |
| SCHEMBL7988202 | 0.81 | ALDH1A1 (0.46) | ALDH1A1HSD17B10TDP1PTGS2KDM4E | |
| SCHEMBL17627905 | 0.79 | ALDH1A1 (0.47) | ALDH1A1HSD17B10TDP1PTGS2KDM4E | |
| SCHEMBL25351523 | 0.78 | ALDH1A1 (0.56) | ALDH1A1HSD17B10TDP1PTGS2KDM4E | |
| SCHEMBL30438781 | 0.78 | ALDH1A1 (0.56) | ALDH1A1HSD17B10TDP1PTGS2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112279831-A | Novel method for promoting photosensitive oxidation to remove 1, 2-mercaptoethanol acetal protective group by using visible light irradiation | 兰州大学 | 2021-01-29 | — | — | CN | disclosed |
| CN-105579450-B | Novel indolizine compounds, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2017-12-12 | — | — | CN | disclosed |
| CN-104144930-B | New indolizine derivatives, method for preparing same and pharmaceutical compositions containing same | 瑟维尔实验室 | 2017-02-22 | — | — | CN | disclosed |
| CN-104144930-A | New indolizine derivatives, method for preparing same and pharmaceutical compositions containing same | SERVIER LAB | 2014-11-12 | — | — | CN | disclosed |
| CN-1119342-C | Process for preparing bromo-ortho-piperonaldehyde | WANG SHIGUO (CN) | 2003-08-27 | — | — | CN | disclosed |
| CN-1326933-A | Process for preparing bromo-ortho-piperonaldehyde | WANG SHIGUO (CN) | 2001-12-19 | — | — | CN | disclosed |
| EP-0285267-A2 | Pyridine derivatives for treatment and prevention of liver damage, and their preparation | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-10-05 | — | — | EP | disclosed |
| EP-0002327-B1 | PHARMACOLOGICALLY ACTIVE 6-LOWER ALKYL-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINES, METHOD OF PREPARING THEM AND INTERMEDIATES | SMITHKLINE BECKMAN CORPORATION (US) | 1982-08-04 | — | — | EP | disclosed |
| US-4342686-A | Intermediates for preparing 6-lower alkyl-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines | SMITHKLINE CORPORATION (US) | 1982-08-03 | — | — | US | disclosed |
| US-4265889-A | DOPAMINERGIC, HYPOTENSIVE | SMITHKLINE CORPORATION (US) | 1981-05-05 | — | — | US | disclosed |
| US-4165372-A | 6-Carboxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine compounds and use as dopaminergic agents | SMITHKLINE CORPORATION (US) | 1979-08-21 | — | — | US | disclosed |
| EP-0002327-A1 | Pharmacologically active 6-lower alkyl-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines, method of preparing them and intermediates | SMITHKLINE BECKMAN CORPORATION (US) | 1979-06-13 | — | — | EP | disclosed |