⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL570696 | 0.69 | — | — | |
| SCHEMBL1951265 | 0.67 | — | — | |
| SCHEMBL1951911 | 0.67 | — | — | |
| SCHEMBL57048 | 0.67 | — | — | |
| SCHEMBL17603211 | 0.65 | — | — | |
| SCHEMBL27800994 | 0.65 | — | — | |
| SCHEMBL4041909 | 0.62 | — | — | |
| SCHEMBL1023999 | 0.61 | — | — | |
| SCHEMBL1483243 | 0.61 | — | — | |
| SCHEMBL4041067 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109943545-B | Method for synthesizing compound by directionally modifying acyltransferase structural domain | 浙江大学 | 2021-08-03 | — | — | CN | claimed |
| EP-2329018-B1 | METHOD FOR THE ANNOTATION OF NATURAL PRODUCT GENE-CLUSTERS AND FOR THE GENERATION OF NOVEL BIOLOGICALLY ACTIVE CHEMICAL ENTITIES FROM DNA SEQUENCES IN SILICO | GENQUAD AG (CH) | 2014-09-10 | — | — | EP | claimed |
| EP-2329018-A1 | METHOD FOR THE ANNOTATION OF NATURAL PRODUCT GENE-CLUSTERS AND FOR THE GENERATION OF NOVEL BIOLOGICALLY ACTIVE CHEMICAL ENTITIES FROM DNA SEQUENCES IN SILICO | Novalis Ltd. (HR) | 2011-06-08 | — | — | EP | claimed |
| WO-2009130520-A1 | METHOD FOR THE ANNOTATION OF NATURAL PRODUCT GENE-CLUSTERS AND FOR THE GENERATION OF NOVEL BIOLOGICALLY ACTIVE CHEMICAL ENTITIES FROM DNA SEQUENCES IN SILICO | NOVALIS LTD. (HR) | 2009-10-29 | — | — | WO | claimed |
| US-5449612-A | Process for identifying candida by means of chromogenic substances | SERBIO (FR) | 1995-09-12 | — | — | US | claimed |
| CN-117487837-A | Gene editing plasmid of rare actinomycetes and application thereof | 华东理工大学 | 2024-02-02 | — | — | CN | disclosed |
| CN-107083412-B | Application of medium-short chain acyl coenzyme A synthetase | 刘超 | 2021-05-28 | — | — | CN | disclosed |
| US-20200332324-A1 | ENGINEERING POLYKETIDE SYNTHASE IN CYANOBACTERIA | UNIV CALIFORNIA (US) | 2020-10-22 | — | — | US | disclosed |
| EP-3385386-A1 | CARRIMYCIN BIOSYNTHETIC GENE CLUSTER | Shenyang Fuyang Pharmaceutical Technology Co., Ltd. (CN) | 2018-10-10 | — | — | EP | disclosed |
| EP-1905833-B1 | Polypeptides involved in the biosynthesis of spiramycins, nucleotide sequences coding these polypeptides and their uses | AVENTIS PHARMA SA (FR) | 2015-08-12 | — | — | EP | disclosed |
| EP-2329018-B1 | METHOD FOR THE ANNOTATION OF NATURAL PRODUCT GENE-CLUSTERS AND FOR THE GENERATION OF NOVEL BIOLOGICALLY ACTIVE CHEMICAL ENTITIES FROM DNA SEQUENCES IN SILICO | GENQUAD AG (CH) | 2014-09-10 | — | — | EP | disclosed |
| US-8759031-B2 | Type I polyketide synthase extender units | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2014-06-24 | — | — | US | disclosed |
| US-6100394-A | Long-lived homogenous oxidation catalysts | CARNEGIE MELLON UNIVERSITY (US) | 2000-08-08 | — | — | US | disclosed |
| WO-2000020601-A2 | POLYKETIDE SYNTHASE ENZYMES AND RECOMBINANT DNA CONSTRUCTS THEREFOR | KOSAN BIOSCIENCES, INC. (US) | 2000-04-13 | — | — | WO | disclosed |
| EP-0509769-B1 | Heterocyclic amides having HLE inhibiting activity | ZENECA LTD (GB) | 1996-09-11 | — | — | EP | disclosed |
| US-5521179-A | Heterocyclic amides | ZENECA LIMITED (GB) | 1996-05-28 | — | — | US | disclosed |
| US-5472851-A | Converting plasminogen to plasmin and the assaying plasmin resulting from said conversion; inhibiting plsma proteins alpha2-antiplsmin and alpha2-macroglobulin by contact with metalloproteinase | SERBIO (FR) | 1995-12-05 | — | — | US | disclosed |
| US-5449612-A | Process for identifying candida by means of chromogenic substances | SERBIO (FR) | 1995-09-12 | — | — | US | disclosed |
| US-5225532-A | SYMMETRICAL BIPEPTIDES CONTAINING A POLYALKYLENE GLYCOL RESIDUE, METHOD OF PREPARATION AND USE IN THE ASSAY OF PROTEASES | SERBIO (FR) | 1993-07-06 | — | — | US | disclosed |
| EP-0509769-A2 | Heterocyclic amides having HLE inhibiting activity | ZENECA LIMITED (GB) | 1992-10-21 | — | — | EP | disclosed |