SCHEMBL10620588

SCHEMBL10620588

O=P(O)(O)C(CCC(CCC(c1ccccc1)(c1ccccc1)P(=O)(O)O)(c1ccccc1)P(=O)(O)O)(CCC(c1ccccc1)(c1ccccc1)P(=O)(O)O)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 3/20 0.47
PGK1 P00558 5/20 0.40
PGK2 P07205 5/20 0.40
FDPS P14324 2/20 0.39
PTPN5 P54829 2/20 0.39
SRC P12931 1/20 0.35
CYP1A2 P05177 1/20 0.35
CFTR P13569 1/20 0.35
CA2 P00918 1/20 0.34
CA4 P22748 1/20 0.34
CA5A P35218 1/20 0.34
LAP3 P28838 3/20 0.34
ANPEP P15144 1/20 0.34
TSHR P16473 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8586130 0.79 PTPN1 (0.48) PTPN1PGK1PGK2FDPSPTPN5
SCHEMBL874648 0.79 PTPN1 (0.48) PTPN1PGK1PGK2FDPSPTPN5
SCHEMBL11406548 0.76 PTPN1 (0.46) PTPN1PGK1PGK2FDPSTSHR
SCHEMBL11475619 0.75 FDPS (0.47) PTPN1FDPS
SCHEMBL3504658 0.75 PTPN1 (0.52) PTPN1PGK1PGK2FDPSPTPN5
SCHEMBL1556937 0.75 PTPN1 (0.52) PTPN1PGK1PGK2FDPSPTPN5
SCHEMBL4159184 0.75 PTPN1 (0.52) PTPN1PGK1PGK2FDPSPTPN5
SCHEMBL8538943 0.75 PTPN1 (0.52) PTPN1PGK1PGK2FDPSPTPN5
Hydrogen Peroxide SCHEMBL8609891 0.75 PTPN1 (0.52) PTPN1PGK1PGK2FDPSPTPN5
SCHEMBL8353857 0.75 PTPN1 (0.52) PTPN1PGK1PGK2FDPSPTPN5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4698422-A Triphos and tetraphos gold compounds and ligands SMITHKLINE BECKMAN CORPORATION (US) 1987-10-06 US claimed
EP-0202854-A2 Phosphine gold compounds SMITHKLINE BEECHAM CORPORATION (US) 1986-11-26 EP claimed
US-4758589-A Tetraphosphine-coordinated gold(I) complexes SMITHKLINE BECKMAN CORPORATION (US) 1988-07-19 US disclosed
US-4698422-A Triphos and tetraphos gold compounds and ligands SMITHKLINE BECKMAN CORPORATION (US) 1987-10-06 US disclosed
US-4675427-A ANTITUMOR AGENTS SMITH KLINE BECKMAN CORPORATION (US) 1987-06-23 US disclosed
EP-0202854-A2 Phosphine gold compounds SMITHKLINE BEECHAM CORPORATION (US) 1986-11-26 EP disclosed