Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.50 |
| ▸ | TACR3 | P29371 | 3/20 | 0.48 |
| ▸ | NAAA | Q02083 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 2/20 | 0.45 |
| ▸ | TLR2 | O60603 | 1/20 | 0.44 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28702567 | 0.82 | POLB (0.48) | MMETACR3NAAAPOLBASAH1 | |
| SCHEMBL8249158 | 0.81 | MME (0.53) | MMENAAAPOLBACEALDH1A1 | |
| SCHEMBL11031006 | 0.81 | POLB (0.52) | MMETACR3NAAAPOLBASAH1 | |
| SCHEMBL5869451 | 0.81 | MME (0.53) | MMENAAAPOLBACEALDH1A1 | |
| SCHEMBL10349304 | 0.79 | POLB (0.47) | TACR3NAAAPOLBALDH1A1CNR2 | |
| SCHEMBL2024979 | 0.79 | TACR3 (0.55) | TACR3NAAAPOLBASAH1ALDH1A1 | |
| SCHEMBL2021335 | 0.79 | TACR3 (0.55) | TACR3NAAAPOLBASAH1ALDH1A1 | |
| SCHEMBL15093649 | 0.79 | TACR3 (0.55) | TACR3NAAAPOLBASAH1ALDH1A1 | |
| SCHEMBL15093655 | 0.79 | TACR3 (0.55) | TACR3NAAAPOLBASAH1ALDH1A1 | |
| SCHEMBL15093823 | 0.79 | TACR3 (0.55) | TACR3NAAAPOLBASAH1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792555-A | DESENSITIZERS; ANTIINFLAMMATORY AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1988-12-20 | — | — | US | disclosed |