Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.30 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10805069 | 0.87 | SKP2 (0.45) | KDM4ETDP1ALDH1A1CYP3A4MAPT | |
| SCHEMBL8977699 | 0.81 | CXCR4 (0.34) | SPHK1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL24603067 | 0.81 | KDM4E (0.45) | KDM4ESLC6A4SLC6A2 | |
| SCHEMBL28136200 | 0.79 | SKP2 (0.50) | KDM4ETDP1ALDH1A1CYP3A4MAPT | |
| SCHEMBL15826731 | 0.78 | CXCR4 (0.31) | SPHK1 | |
| SCHEMBL40067 | 0.78 | IDO1 (0.32) | SPHK1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL29398175 | 0.78 | IDO1 (0.32) | SPHK1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL10943037 | 0.78 | ALDH1A1 (0.36) | ALDH1A1MAPTSPHK1SLC6A4SLC6A2 | |
| SCHEMBL10942833 | 0.77 | ALDH1A1 (0.37) | KDM4ETDP1ALDH1A1CYP3A4TSHR | |
| SCHEMBL28028910 | 0.76 | TDP1 (0.37) | KDM4ETDP1ALDH1A1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4786751-A | POLYURETHANES | BAYER AKTIENGESELLSCHAFT (DE) | 1988-11-22 | — | — | US | disclosed |
| EP-0154768-B1 | PROCESS FOR THE PREPARATION OF POLYURETHANES, POLYURETHANES HAVING AROMATIC AMINO TERMINAL GROUPS AND THEIR USE | BAYER AG (DE) | 1988-05-25 | — | — | EP | disclosed |
| US-4720582-A | Diamines and a process for their production | BAYER AKTIENGESELLSCHAFT (DE) | 1988-01-19 | — | — | US | disclosed |
| EP-0150005-B1 | MAGNETIC STORAGE MEDIUM | Agfa-Gevaert AG (DE) | 1987-09-23 | — | — | EP | disclosed |
| US-4677030-A | POLYUREA-URETHANE BINDER | AGFA GEVAERT AKTIENGESELLSCHAFT (DE) | 1987-06-30 | — | — | US | disclosed |
| EP-0113044-B1 | DIISOCYANATES OR MIXTURES OF DIISOCYANATES, PROCESS FOR THEIR PRODUCTION, AS WELL AS THEIR USE IN THE PRODUCTION OF POLYURETHANES | BAYER AG (DE) | 1986-09-03 | — | — | EP | disclosed |
| US-4574147-A | Process for the production of polyurethanes, polyurethanes containing terminal aromatic amino groups and their use | BAYER AKTIENGESELLSCHAFT (DE) | 1986-03-04 | — | — | US | disclosed |
| EP-0104396-B1 | PROCESS FOR PREPARATION OF DIAMINES OR MIXTURES OF DIAMINES | BAYER AG (DE) | 1985-11-13 | — | — | EP | disclosed |
| EP-0154768-A1 | Process for the preparation of polyurethanes, polyurethanes having aromatic amino terminal groups and their use | BAYER AG (DE) | 1985-09-18 | — | — | EP | disclosed |
| EP-0150005-A1 | Magnetic storage medium | Agfa-Gevaert AG (DE) | 1985-07-31 | — | — | EP | disclosed |
| EP-0113044-A2 | Diisocyanates or mixtures of diisocyanates, process for their production, as well as their use in the production of polyurethanes | BAYER AG (DE) | 1984-07-11 | — | — | EP | disclosed |
| EP-0104396-A1 | Process for preparation of diamines or mixtures of diamines | BAYER AG (DE) | 1984-04-04 | — | — | EP | disclosed |