Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.60 |
| ▸ | HPGD | P15428 | 9/20 | 0.60 |
| ▸ | GAA | P10253 | 4/20 | 0.60 |
| ▸ | GLA | P06280 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | CASP1 | P29466 | 3/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RBP4 | P02753 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10620212 | 0.86 | ALDH1A1 (0.63) | ALDH1A1KDM4EHPGDGAAGLA | |
| SCHEMBL10620100 | 0.84 | ALDH1A1 (0.60) | ALDH1A1KDM4EHPGDGAAGLA | |
| SCHEMBL10617333 | 0.83 | ALDH1A1 (0.56) | ALDH1A1KDM4EHPGDGAAGLA | |
| SCHEMBL10617083 | 0.81 | ALDH1A1 (0.50) | ALDH1A1GAAHSD17B10SMN1; SMN2MAPT | |
| SCHEMBL10617037 | 0.74 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDGAAGLA | |
| SCHEMBL9140749 | 0.73 | ALDH1A1 (0.48) | ALDH1A1KDM4EHPGDGAAGLA | |
| SCHEMBL9300919 | 0.73 | KDM4E (0.66) | ALDH1A1KDM4EHPGDGAAGLA | |
| SCHEMBL18366709 | 0.70 | ALDH1A1 (0.51) | ALDH1A1KDM4EHPGDGAAGLA | |
| SCHEMBL16759976 | 0.70 | ALDH1A1 (0.63) | ALDH1A1GAAHSD17B10SMN1; SMN2MAPT | |
| SCHEMBL9677390 | 0.69 | ALDH1A1 (0.40) | ALDH1A1KDM4EHPGDGAAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0286145-A2 | 3-Heterocyclylthiomethyl cephalosporins | SANKEI PHARMACEUTICAL COMPANY LIMITED (JP) | 1988-10-12 | — | — | EP | disclosed |