Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ABL1 | P00519 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 8/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10520788 | 0.89 | HDAC8 (0.44) | HDAC8LMNAKDM4EABL1POLB | |
| SCHEMBL10619222 | 0.82 | ABL1 (0.65) | HDAC8LMNAKDM4EABL1POLB | |
| SCHEMBL3607773 | 0.81 | KMT2A (0.68) | HDAC8LMNAKDM4EABL1POLB | |
| SCHEMBL10519037 | 0.80 | MEN1 (0.51) | HDAC8LMNAKDM4EABL1POLB | |
| SCHEMBL10520148 | 0.80 | IKBKE (0.45) | HDAC8LMNAKDM4EABL1POLB | |
| SCHEMBL10520562 | 0.80 | KMT2A (0.53) | HDAC8LMNAKDM4EABL1POLB | |
| SCHEMBL10619228 | 0.79 | HDAC8 (0.45) | HDAC8LMNAKDM4EABL1POLB | |
| SCHEMBL3602480 | 0.78 | KDM4E (0.36) | LMNAKDM4EABL1POLBALDH1A1 | |
| SCHEMBL3612918 | 0.77 | MAPT (0.40) | LMNAKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL3605679 | 0.77 | ATP4A (0.38) | LMNAKDM4EALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4720493-A | Thienylthiazole compounds | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1988-01-19 | — | — | US | disclosed |
| EP-0183191-A1 | Thienylthiazole compounds | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1986-06-04 | — | — | EP | disclosed |