SCHEMBL10622271

SCHEMBL10622271

C(=Cc1ccccc1N=Nc1cccc2ccccc12)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CHAT P28329 5/20 0.47
POLB P06746 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
PTGS1 P23219 1/20 0.42
PTGS2 P35354 1/20 0.42
TRPA1 O75762 1/20 0.42
NFE2L2 Q16236 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14690157 0.86 NFE2L2 (0.54) CHATTRPA1NFE2L2
SCHEMBL14690153 0.86 NFE2L2 (0.54) CHATTRPA1NFE2L2
SCHEMBL14690155 0.86 NFE2L2 (0.54) CHATTRPA1NFE2L2
Benzene SCHEMBL28841289 0.80 CHAT (0.68) CHATPTGS1PTGS2
SCHEMBL6051064 0.80 CHAT (0.68) CHATPTGS1PTGS2
SCHEMBL29794070 0.80 CHAT (0.68) CHATPTGS1PTGS2
SCHEMBL1782982 0.80 CHAT (0.68) CHATPTGS1PTGS2
SCHEMBL2774767 0.80 CHAT (0.68) CHATPTGS1PTGS2
Benzene SCHEMBL7716364 0.80 CYP1A2 (0.56) CHATPOLBL3MBTL1
Benzene SCHEMBL11235066 0.80 CYP1A2 (0.56) CHATPOLBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4793977-A MATRIX OF BONDED IONOMER, IONIC INDICATOR DYE AND BASE; INTERNAL COMBUSTION ENGINES; TESTING ACID BUILD-UP CAPE COD RESEARCH, INC. (US) 1988-12-27 US disclosed