Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 12/20 | 0.70 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 10/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 8/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10625534 | 1.00 | EPHX1 (0.70) | EPHX1POLBRAB9ASMN1; SMN2EPHX2 | |
| SCHEMBL10622356 | 0.98 | EPHX1 (0.68) | EPHX1POLBRAB9ASMN1; SMN2EPHX2 | |
| SCHEMBL5641433 | 0.83 | EPHX1 (1.00) | EPHX1POLBRAB9ASMN1; SMN2EPHX2 | |
| SCHEMBL13756244 | 0.80 | EPHX1 (0.86) | EPHX1RAB9ASMN1; SMN2EPHX2NPC1 | |
| SCHEMBL13756248 | 0.78 | EPHX1 (0.83) | EPHX1RAB9ASMN1; SMN2EPHX2NPC1 | |
| SCHEMBL812273 | 0.76 | RAB9A (1.00) | EPHX1POLBRAB9ASMN1; SMN2EPHX2 | |
| SCHEMBL4266873 | 0.76 | RAB9A (1.00) | EPHX1POLBRAB9ASMN1; SMN2EPHX2 | |
| SCHEMBL9599607 | 0.75 | EPHX1 (0.65) | EPHX1POLBRAB9ASMN1; SMN2EPHX2 | |
| SCHEMBL10669957 | 0.75 | POLB (0.59) | EPHX1POLBRAB9ASMN1; SMN2EPHX2 | |
| SCHEMBL10678103 | 0.75 | POLB (0.59) | EPHX1POLBRAB9ASMN1; SMN2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4728355-A | RETARDING SENESCENCE IN SOYBEANS AND COTTON | FMC CORPORATION (US) | 1988-03-01 | — | — | US | claimed |