SCHEMBL10623596

SCHEMBL10623596

CCC(=O)/C(C)=C/C=C(\C)CCC=C(C)C

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.55
KDM4E B2RXH2 1/20 0.48
ATM Q13315 1/20 0.48
FNTA P49354 2/20 0.47
FNTB P49356 2/20 0.47
POLB P06746 1/20 0.47
KMT2A Q03164 3/20 0.47
ALOX15 P16050 3/20 0.44
SQLE Q14534 2/20 0.44
NR1I2 O75469 1/20 0.44
LMNA P02545 1/20 0.44
PGR P06401 1/20 0.44
MEN1 O00255 2/20 0.44
CYP3A4 P08684 2/20 0.44
MAPT P10636 2/20 0.42
UGT1A1 P22309 1/20 0.42
TRPA1 O75762 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10623599 1.00 ALDH1A1 (0.55) ALDH1A1KDM4EATMFNTAFNTB
SCHEMBL2965140 0.82 ALDH1A1 (0.61) ALDH1A1KDM4EATMFNTAFNTB
SCHEMBL8705357 0.82 ALDH1A1 (0.61) ALDH1A1KDM4EATMFNTAFNTB
SCHEMBL2965141 0.82 ALDH1A1 (0.61) ALDH1A1KDM4EATMFNTAFNTB
SCHEMBL10422680 0.80 ALDH1A1 (0.61) ALDH1A1KDM4EATMPOLBKMT2A
SCHEMBL14373919 0.78 NR1I2 (0.71) ALDH1A1KDM4EATMFNTAFNTB
SCHEMBL16387740 0.75 ALDH1A1 (0.61) ALDH1A1KDM4EATMFNTAFNTB
SCHEMBL2861207 0.73 NR1I2 (0.61) ALDH1A1KDM4EATMFNTAFNTB
SCHEMBL2861204 0.73 NR1I2 (0.61) ALDH1A1KDM4EATMFNTAFNTB
Citral SCHEMBL2473483 0.72 ALDH1A1 (0.91) ALDH1A1KDM4EATMFNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0172519-B1 PROCESS FOR THE PREPARATION OF IONONES BASF Aktiengesellschaft (DE) 1988-11-23 EP disclosed
EP-0172519-A1 Process for the preparation of ionones BASF Aktiengesellschaft (DE) 1986-02-26 EP disclosed