Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.44 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | PPOX | P50336 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10621094 | 0.83 | FFAR1 (0.43) | LMNAFFAR1AGPAT2KMT2AMEN1 | |
| SCHEMBL10727592 | 0.75 | AGPAT2 (0.51) | PTGS2FFAR1AGPAT2KMT2AMEN1 | |
| SCHEMBL10608354 | 0.74 | FFAR1 (0.42) | FFAR1KMT2AMEN1TTRPPOX | |
| SCHEMBL10621865 | 0.72 | CBX7 (0.47) | FFAR1KMT2AMEN1TTRPPOX | |
| SCHEMBL10724906 | 0.72 | MEN1 (0.52) | FFAR1AGPAT2KMT2AMEN1TTR | |
| SCHEMBL11123547 | 0.72 | LMNA (0.51) | PTGS2LMNAKMT2AMEN1TDP1 | |
| SCHEMBL9711441 | 0.72 | FFAR1 (0.54) | LMNAFFAR1KMT2AMEN1TTR | |
| SCHEMBL8696452 | 0.71 | FFAR1 (0.46) | LMNAFFAR1KMT2AMEN1TTR | |
| SCHEMBL10965377 | 0.70 | MEN1 (0.61) | LMNAFFAR1KMT2AMEN1TTR | |
| SCHEMBL8748928 | 0.70 | FFAR1 (0.54) | LMNAFFAR1KMT2AMEN1TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4746351-A | POSTEMERGENCE | PPG INDUSTRIES, INC. (US) | 1988-05-24 | — | — | US | disclosed |
| EP-0245804-A2 | Herbicidally active substituted phenoxy benzoxazole (or benzothiazole) compounds | PPG INDUSTRIES, INC. (US) | 1987-11-19 | — | — | EP | disclosed |