Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VHL | P40337 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 3/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | BDKRB2 | P30411 | 2/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10624289 | 0.88 | F2 (0.38) | F2OPRD1ACE | |
| SCHEMBL20782464 | 0.85 | F2 (0.37) | VHLF2OPRD1ACE | |
| SCHEMBL29795307 | 0.84 | VHL (0.40) | VHLCHRM2CHRM4CHRM3CHRM1 | |
| Rotigaptide SCHEMBL20547994 | 0.79 | VHL (0.49) | VHLOPRD1BDKRB2 | |
| Rotigaptide SCHEMBL20547993 | 0.79 | VHL (0.49) | VHLOPRD1BDKRB2 | |
| SCHEMBL16925996 | 0.79 | VHL (0.47) | VHLOPRD1BDKRB2 | |
| Rotigaptide SCHEMBL29359046 | 0.79 | VHL (0.49) | VHLOPRD1BDKRB2 | |
| SCHEMBL19381802 | 0.79 | VHL (0.47) | VHLOPRD1BDKRB2 | |
| SCHEMBL31327461 | 0.77 | VHL (0.54) | VHLF2OPRD1BDKRB2ACE | |
| SCHEMBL19381804 | 0.74 | VHL (0.51) | VHLOPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62059296-A | — | — | None | — | — | JP | disclosed |
| US-4775743-A | ANTIAGGLOMERANTS | GREEN CROSS CORPORATION (JP) | 1988-10-04 | — | — | US | disclosed |
| EP-0214659-A2 | Peptide derivatives, process for the production thereof and pharmaceutical compositions containing same | GREEN CROSS CORPORATION (JP) | 1987-03-18 | — | — | EP | disclosed |
| JP-S6259296-A | PEPTIDE DERIVATIVE | GREEN CROSS CORP:THE | 1987-03-14 | — | — | JP | disclosed |