Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 2/20 | 0.64 |
| ▸ | RHEB | Q15382 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 4/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.44 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.44 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.44 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.44 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.44 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.44 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9389526 | 0.78 | PSMB8 (0.49) | PSMB8RHEBGAAHTTAR | |
| SCHEMBL9389516 | 0.78 | PSMB8 (0.49) | PSMB8RHEBGAAHTTAR | |
| SCHEMBL29935431 | 0.78 | PSMB8 (0.56) | PSMB8RHEBGAAHTTGRIA1 | |
| SCHEMBL10958881 | 0.78 | PSMB8 (1.00) | PSMB8MEN1NPC1RAB9AKMT2A | |
| SCHEMBL10958865 | 0.78 | PSMB8 (0.75) | PSMB8RHEBGAAMEN1KMT2A | |
| Lithium Ion SCHEMBL29942329 | 0.77 | PSMB8 (0.54) | PSMB8RHEBGAAHTTGRIA1 | |
| SCHEMBL5904354 | 0.77 | PSMB8 (0.54) | PSMB8RHEBARLMNARAB9A | |
| Lithium SCHEMBL30899067 | 0.77 | PSMB8 (0.54) | PSMB8RHEBGAAHTTGRIA1 | |
| SCHEMBL29216479 | 0.77 | PSMB8 (0.54) | PSMB8RHEBGAAHTTGRIA1 | |
| SCHEMBL6311477 | 0.73 | GAA (0.62) | RHEBGAAHTTARGRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4780473-A | BENZIMIDAZOLE OR IMIDAZOPYRIDINE DERIVATIVES | SCHERING AGROCHEMICALS LTD. (GB) | 1988-10-25 | — | — | US | disclosed |
| EP-0219192-A2 | Fungicides | SCHERING AGROCHEMICALS LIMITED (GB) | 1987-04-22 | — | — | EP | disclosed |