Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 2/20 | 0.49 |
| ▸ | RHEB | Q15382 | 3/20 | 0.38 |
| ▸ | AR | P10275 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ATP4A | P20648 | 3/20 | 0.33 |
| ▸ | ATP4B | P51164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.31 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.31 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.31 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.31 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.31 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9389516 | 0.94 | PSMB8 (0.49) | PSMB8RHEBARGAAKDM4E | |
| SCHEMBL10627035 | 0.78 | PSMB8 (0.64) | PSMB8RHEBARGAAMEN1 | |
| SCHEMBL5904354 | 0.69 | PSMB8 (0.54) | PSMB8RHEBARKDM4EMAPT | |
| SCHEMBL29935431 | 0.67 | PSMB8 (0.56) | PSMB8RHEBGAAKDM4EMEN1 | |
| SCHEMBL10958881 | 0.66 | PSMB8 (1.00) | PSMB8KDM4EMEN1MAPTKMT2A | |
| SCHEMBL10958865 | 0.66 | PSMB8 (0.75) | PSMB8RHEBGAAKDM4EMEN1 | |
| Lithium SCHEMBL30899067 | 0.65 | PSMB8 (0.54) | PSMB8RHEBGAAKDM4EMEN1 | |
| Lithium Ion SCHEMBL29942329 | 0.65 | PSMB8 (0.54) | PSMB8RHEBGAAKDM4EMEN1 | |
| SCHEMBL29216479 | 0.65 | PSMB8 (0.54) | PSMB8RHEBGAAKDM4EMEN1 | |
| SCHEMBL22853019 | 0.65 | TRPV4 (0.39) | MEN1MAPTKMT2ANPSR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994018173-A1 | BENZIMIDAZOLESULFONIC ACID DERIVATIVES AS MICROBICIDES | CIBA-GEIGY AG (CH) | 1994-08-18 | — | — | WO | disclosed |