SCHEMBL10627353

SCHEMBL10627353

CSc1c(SC#N)nc(Cl)nc1SC#N

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.34
GLA P06280 1/20 0.34
TSHR P16473 1/20 0.34
HTT P42858 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL397101 0.90 MEN1 (0.32) MEN1GLATSHRHTTKMT2A
SCHEMBL10748182 0.72 CSNK1A1 (0.36) MEN1GLATSHRHTTKMT2A
Ammonia Solution, Strong SCHEMBL543592 0.69 USP2 (0.39)
SCHEMBL9618980 0.65 CSNK1A1 (0.40)
SCHEMBL1397057 0.64 ALDH1A1 (0.39) TSHR
SCHEMBL9618757 0.63 CSNK1A1 (0.38) MEN1HTTKMT2A
SCHEMBL9618767 0.63 CSNK1A1 (0.38) KMT2A
SCHEMBL9618904 0.63 CSNK1A1 (0.38)
SCHEMBL8986160 0.63 MEN1 (0.60) MEN1GLATSHRHTTKMT2A
Ammonia Solution, Strong SCHEMBL543591 0.62 USP2 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4774335-A MONO THIOCYANATION OF HALO PYRIMIDINES MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1988-09-27 US disclosed
US-4652569-A Thiocyanopyrimidine, agricultural and horticultural fungicide containing same MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1987-03-24 US disclosed