Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9804706 | 0.89 | TSHR (0.54) | TSHRLMNAALDH1A1CNR2AOC3 | |
| SCHEMBL11875496 | 0.86 | TSHR (0.41) | TSHRLMNAALDH1A1CNR2AOC3 | |
| SCHEMBL12353952 | 0.83 | TSHR (0.45) | TSHRLMNAALDH1A1CNR2AOC3 | |
| SCHEMBL27461982 | 0.80 | TSHR (0.42) | TSHRLMNAALDH1A1OPRM1DRD3 | |
| SCHEMBL321715 | 0.78 | TSHR (0.43) | TSHRLMNAALDH1A1AOC3MGLL | |
| SCHEMBL1093442 | 0.76 | ALDH1A1 (0.47) | TSHRLMNAALDH1A1AOC3KDM4E | |
| Methane SCHEMBL2487926 | 0.76 | TSHR (0.42) | TSHRLMNAALDH1A1AOC3MGLL | |
| SCHEMBL3443600 | 0.76 | MEN1 (0.43) | TSHRLMNAALDH1A1AOC3CARM1 | |
| SCHEMBL13318929 | 0.75 | TSHR (0.41) | TSHRLMNAALDH1A1AOC3L3MBTL1 | |
| SCHEMBL28280605 | 0.74 | TSHR (0.48) | TSHRLMNAALDH1A1CNR2AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4732914-A | Prostacyclin analogs | THE UPJOHN COMPANY (US) | 1988-03-22 | — | — | US | disclosed |
| US-4705806-A | Prostacyclin analogs | PHARMACIA & UPJOHN COMPANY | 1987-11-10 | — | — | US | disclosed |
| US-4490537-A | Enlarged-hetero-ring prostacyclin analogs | THE UPJOHN COMPANY (US) | 1984-12-25 | — | — | US | disclosed |
| US-4490549-A | Enlarged-hetero-ring prostacyclin analogs | THE UPJOHN COMPANY (US) | 1984-12-25 | — | — | US | disclosed |
| US-4490538-A | Enlarged-hetero-ring prostacyclin analogs | THE UPJOHN COMPANY (US) | 1984-12-25 | — | — | US | disclosed |
| US-4490548-A | Enlarged-hetero-ring prostacyclin analogs | THE UPJOHN COMPANY (US) | 1984-12-25 | — | — | US | disclosed |
| US-4243611-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1981-01-06 | — | — | US | disclosed |
| US-4238414-A | 2-Decarboxy-2-aminomethyl-6a-carba-PGI2 compounds | THE UPJOHN COMPANY (US) | 1980-12-09 | — | — | US | disclosed |
| US-4235779-A | Bicyclic lactones | THE UPJOHN COMPANY (US) | 1980-11-25 | — | — | US | disclosed |
| US-4228104-A | PROSTAGLANDIN DERIVATIVES | THE UPJOHN COMPANY (US) | 1980-10-14 | — | — | US | disclosed |
| US-3969396-A | 8β, 11β, 12α-PGE2 compounds | THE UPJOHN COMPANY (US) | 1976-07-13 | — | — | US | disclosed |
| US-3965118-A | Lactone intermediates | THE UPJOHN COMPANY (US) | 1976-06-22 | — | — | US | disclosed |
| US-3954835-A | 4,5-Cis-didehydro-PGF1 compounds | THE UPJOHN COMPANY (US) | 1976-05-04 | — | — | US | disclosed |
| US-3944595-A | PROSTAGLANDIN | THE UPJOHN COMPANY (US) | 1976-03-16 | — | — | US | disclosed |
| US-3933900-A | ANTIULCER, ANTICOAGULANTS, NASAL PATENCY, LABOR INDUCERS, WOUND HEALING | THE UPJOHN COMPANY (US) | 1976-01-20 | — | — | US | disclosed |
| US-3933899-A | ANTIULCER, ANTICOAGULANTS, NASAL PATENCY, LABOR INDUCERS, WOUND HEALING | THE UPJOHN COMPANY (US) | 1976-01-20 | — | — | US | disclosed |
| US-3933898-A | ANTIULCER, ANTICOAGULANTS, NASAL PATENCY, LABOR INDUCERS, WOUND HEALING | THE UPJOHN COMPANY (US) | 1976-01-20 | — | — | US | disclosed |
| US-3933895-A | PROSTAGLANDINS, ANTIULCER, ANTICOAGULANTS, NASAL PATENCY, LABOR INDUCERS, WOUND HEALING | THE UPJOHN COMPANY (US) | 1976-01-20 | — | — | US | disclosed |
| US-3933896-A | ANTICOAGULANTS, ASTHMA, LABOR INDUCERS, CERVICAL DILATION | THE UPJOHN COMPANY (US) | 1976-01-20 | — | — | US | disclosed |
| US-3933897-A | ANTIULCER, ASTHMA, RENAL DYSFUNCTION | THE UPJOHN COMPANY (US) | 1976-01-20 | — | — | US | disclosed |