Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PNP | P00491 | 7/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TYMS | P04818 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HBB | P68871 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6359270 | 0.69 | PNP (0.60) | KDM4EALDH1A1PNPMAPTTYMS | |
| 8-Aminoguanine SCHEMBL21760 | 0.69 | KDM4E (0.60) | KDM4EALDH1A1LMNAGLAPMP22 | |
| SCHEMBL65613 | 0.63 | KDM4E (0.38) | KDM4EALDH1A1GLAMAPTBLM | |
| SCHEMBL9466605 | 0.62 | KDM4E (0.37) | KDM4EALDH1A1GLAMAPTTHRB | |
| SCHEMBL1289589 | 0.61 | MAPT (0.44) | KDM4EALDH1A1LMNAGLAPMP22 | |
| SCHEMBL6356983 | 0.61 | CHUK (0.36) | KDM4EALDH1A1LMNAGLAPMP22 | |
| 8-Aminoguanine SCHEMBL5513816 | 0.60 | KDM4E (0.50) | KDM4EALDH1A1LMNAGLAPMP22 | |
| SCHEMBL19945607 | 0.60 | ALDH1A1 (0.33) | KDM4EALDH1A1MAPT | |
| SCHEMBL29061394 | 0.60 | ALDH1A1 (0.38) | KDM4EALDH1A1LMNAGLAPMP22 | |
| SCHEMBL4002943 | 0.60 | CSNK2A2 (0.35) | KDM4EALDH1A1LMNAGLAPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4746403-A | EMBEDDING A FABRIC IN A SILICATE MATRIC CONTAINING INTERSTITIAL GUADINE OR MULTIAMINE CATIONS | ARMSTRONG WORLD INDUSTRIES, INC. (US) | 1988-05-24 | — | — | US | claimed |