Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | GSR | P00390 | 1/20 | 0.40 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | CPB2 | Q96IY4 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19066306 | 0.93 | APP (0.42) | APPGSRRNPEPBLMPMP22 | |
| SCHEMBL28586829 | 0.86 | APP (0.41) | APPGSRRNPEPBLMPMP22 | |
| SCHEMBL1638487 | 0.83 | LMNA (0.38) | APPBLMLMNASLC6A6CYP2C19 | |
| SCHEMBL1566750 | 0.83 | TP53 (0.53) | TP53GNAI3GNAO1GNAI1 | |
| SCHEMBL4895410 | 0.81 | LMNA (0.36) | APPBLMLMNASLC6A6CYP2C19 | |
| SCHEMBL20495909 | 0.81 | TP53 (0.52) | TP53GNAI3GNAO1GNAI1 | |
| SCHEMBL21357040 | 0.81 | TP53 (0.52) | TP53GNAI3GNAO1GNAI1 | |
| SCHEMBL11305164 | 0.81 | TP53 (0.52) | TP53GNAI3GNAO1GNAI1 | |
| SCHEMBL20495930 | 0.81 | TP53 (0.52) | TP53GNAI3GNAO1GNAI1 | |
| SCHEMBL20495920 | 0.81 | TP53 (0.52) | TP53GNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4728542-A | POLYURETHANES; WATER VAPOR PERMEABLE COATINGS | BAYER AKTIENGESELLSCHAFT (DE) | 1988-03-01 | — | — | US | disclosed |