Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 5/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10633354 | 0.92 | KMT2A (0.48) | TRPV4KMT2AHIF1AEPAS1MAPK1 | |
| SCHEMBL10633376 | 0.82 | POLB (0.50) | KMT2AHIF1AEPAS1MAPK1TSHR | |
| SCHEMBL10627121 | 0.82 | TRPV4 (0.50) | TRPV4PKM | |
| SCHEMBL10628705 | 0.78 | TRPV4 (0.62) | TRPV4KMT2AMAPT | |
| SCHEMBL10682426 | 0.78 | KMT2A (0.55) | KMT2AMAPK1TSHRPOLBPDE4A | |
| SCHEMBL10778015 | 0.76 | TRPV4 (0.52) | TRPV4 | |
| SCHEMBL10627173 | 0.76 | TRPV4 (0.52) | TRPV4HTT | |
| SCHEMBL4176989 | 0.76 | TSHR (0.50) | HIF1AEPAS1MAPK1TSHRPDE4A | |
| SCHEMBL4169818 | 0.76 | KMT2A (0.59) | KMT2AMAPK1TSHRPDE4APDE4B | |
| SCHEMBL10777217 | 0.75 | TRPV4 (0.51) | TRPV4KMT2AHIF1ATSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4720580-A | N-(aminoalkylene)benzenesulfonamides | AMERICAN HOME PRODUCTS CORPORATION (US) | 1988-01-19 | — | — | US | disclosed |