Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.45 |
| ▸ | F2R | P25116 | 2/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | KDM5A | P29375 | 2/20 | 0.44 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.44 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10633798 | 1.00 | HPGD (0.54) | HPGDALDH1A1SMN1; SMN2EPHX1MEN1 | |
| SCHEMBL13618530 | 0.88 | HPGD (0.57) | HPGDALDH1A1EPHX1MEN1KMT2A | |
| SCHEMBL21882669 | 0.81 | KDM5A (0.50) | HPGDALDH1A1EPHX1MEN1KMT2A | |
| SCHEMBL7286378 | 0.81 | HDAC3 (0.51) | HPGDALDH1A1SMN1; SMN2EPHX1EPHX2 | |
| SCHEMBL25911804 | 0.81 | KDM5A (0.50) | HPGDALDH1A1EPHX1MEN1KMT2A | |
| SCHEMBL8848118 | 0.81 | HPGD (0.56) | HPGDALDH1A1EPHX1MEN1KMT2A | |
| SCHEMBL24882522 | 0.80 | KDM5A (0.52) | HPGDALDH1A1EPHX1MEN1KMT2A | |
| SCHEMBL9071922 | 0.80 | EPHX2 (0.57) | HPGDALDH1A1EPHX1MEN1KMT2A | |
| SCHEMBL11024174 | 0.79 | HPGD (0.55) | HPGDALDH1A1SMN1; SMN2EPHX1MEN1 | |
| SCHEMBL9130865 | 0.79 | HPGD (0.55) | HPGDALDH1A1SMN1; SMN2EPHX1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4781977-A | WATER-INSOLUBLE RESIN-SPACER-LIGAND | SANRAKU INCORPORATED (JP) | 1988-11-01 | — | — | US | disclosed |
| EP-0220719-A2 | Cyclodextrin absorbing material and its use | Sanraku Incorporated (JP) | 1987-05-06 | — | — | EP | disclosed |