Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | KDM5A | P29375 | 3/20 | 0.51 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.51 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.51 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.51 |
| ▸ | KDM4A | O75164 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexane Propionic Acid SCHEMBL28302091 | 1.00 | HPGD (0.55) | HPGDLMNAKDM5APHF8KDM2A | |
| SCHEMBL11024174 | 1.00 | HPGD (0.55) | HPGDLMNAKDM5APHF8KDM2A | |
| SCHEMBL31323847 | 1.00 | HPGD (0.55) | HPGDLMNAKDM5APHF8KDM2A | |
| SCHEMBL1595661 | 1.00 | HPGD (0.55) | HPGDLMNAKDM5APHF8KDM2A | |
| SCHEMBL9742678 | 1.00 | HPGD (0.55) | HPGDLMNAKDM5APHF8KDM2A | |
| Cyclohexane Propionic Acid SCHEMBL391087 | 1.00 | HPGD (0.55) | HPGDLMNAKDM5APHF8KDM2A | |
| Cyclohexane Propionic Acid SCHEMBL18344239 | 1.00 | HPGD (0.55) | HPGDLMNAKDM5APHF8KDM2A | |
| Cyclohexane Propionic Acid SCHEMBL7906990 | 0.98 | HPGD (0.53) | HPGDLMNAKDM5APHF8KDM2A | |
| Cyclohexane Propionic Acid SCHEMBL3101046 | 0.98 | HPGD (0.53) | HPGDLMNAKDM5APHF8KDM2A | |
| Cyclohexane Propionic Acid SCHEMBL9101219 | 0.98 | HPGD (0.53) | HPGDLMNAKDM5APHF8KDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5468774-A | Antiinflammatory agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-11-21 | — | — | US | disclosed |
| US-5420153-A | Antiinflammatory agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-05-30 | — | — | US | disclosed |
| US-5366993-A | Antiinflammatory, antifertility | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-11-22 | — | — | US | disclosed |
| WO-1993022305-A1 | TETRONIC, THIOTETRONIC AND TETRAMIC ACID DERIVATIVES AS PHOSPHOLIPASE A2 INHIBITORS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-11-11 | — | — | WO | disclosed |